Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.40 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 3/20 | 0.39 |
| ▸ | CTSK | P43235 | 2/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | REN | P00797 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | AKT1 | P31749 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2014842 | 1.00 | ATM (0.41) | ATMITGA4ITGB7OPRM1OPRD1 | |
| SCHEMBL3807212 | 1.00 | ATM (0.41) | ATMITGA4ITGB7OPRM1OPRD1 | |
| SCHEMBL6316448 | 0.89 | ATM (0.42) | ATMITGA4ITGB7OPRM1OPRD1 | |
| SCHEMBL8907586 | 0.85 | L3MBTL1 (0.43) | ATMITGA4ITGB7OPRM1OPRD1 | |
| SCHEMBL6316889 | 0.85 | ATM (0.43) | ATMITGA4ITGB7OPRM1OPRD1 | |
| SCHEMBL27489128 | 0.85 | ATM (0.43) | ATMITGA4ITGB7OPRM1OPRD1 | |
| SCHEMBL2473923 | 0.85 | ATM (0.43) | ATMITGA4ITGB7OPRM1OPRD1 | |
| SCHEMBL13995754 | 0.83 | REN (0.46) | ATMITGA4ITGB7OPRM1OPRD1 | |
| SCHEMBL24093689 | 0.82 | ATM (0.41) | ATMITGA4ITGB7OPRM1OPRD1 | |
| SCHEMBL7162284 | 0.81 | MAOB (0.45) | ATMITGA4ITGB7OPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011073316-A1 | 4-ARYL-BUTANE-1,3-DIAMIDES | NOVARTIS AG (CH) | 2011-06-23 | — | — | WO | disclosed |