Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.31 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.31 |
| ▸ | TYMS | P04818 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL127785 | 0.73 | CYP3A4 (0.36) | CYP3A4TSHRALDH1A1HPGDKDM4E | |
| SCHEMBL3511272 | 0.72 | TSHR (0.43) | CYP3A4TSHRALDH1A1HPGDKDM4E | |
| SCHEMBL16820850 | 0.67 | ALDH1A1 (0.31) | CYP3A4TSHRALDH1A1HPGDCYP1A2 | |
| SCHEMBL132772 | 0.65 | HSD17B10 (0.42) | CYP3A4TSHRALDH1A1HPGDKDM4E | |
| SCHEMBL22635716 | 0.63 | TSHR (0.38) | CYP3A4TSHRALDH1A1HPGDKDM4E | |
| SCHEMBL2014205 | 0.63 | ALDH1A1 (0.35) | CYP3A4TSHRALDH1A1HPGDCYP1A2 | |
| SCHEMBL2467482 | 0.61 | ALDH1A1 (0.42) | CYP3A4TSHRALDH1A1HPGDKDM4E | |
| SCHEMBL2467480 | 0.61 | TSHR (0.48) | CYP3A4TSHRALDH1A1HPGDKDM4E | |
| SCHEMBL15899340 | 0.60 | ALDH1A1 (0.39) | CYP3A4TSHRALDH1A1HPGDKDM4E | |
| SCHEMBL7539106 | 0.59 | CYP3A4 (0.63) | CYP3A4TSHRALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6746731-B1 | ACHIEVES VERY HIGH MAXIMUM TRANSMISSION AND VERY HIGH CONTRAST AND CONSTANT THRESHOLD VOLTAGE OVER BROAD TEMPERATURE RANGE | CLARIANT GMBH (DE) | 2004-06-08 | — | — | US | disclosed |