SCHEMBL3511272

SCHEMBL3511272

[C]1=Cc2cccc3cccc(c23)C1

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.43
CYP3A4 P08684 2/20 0.43
ALDH1A1 P00352 5/20 0.36
HSD17B10 Q99714 5/20 0.36
HPGD P15428 4/20 0.36
CYP1A2 P05177 3/20 0.36
CYP1A1 P04798 1/20 0.36
CYP1B1 Q16678 1/20 0.36
KDM4E B2RXH2 2/20 0.35
TYMS P04818 1/20 0.33
CYP2C19 P33261 1/20 0.33
LMNA P02545 1/20 0.32
PARP1 P09874 1/20 0.32
MAPK1 P28482 1/20 0.31
ATM Q13315 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17026749 0.83 CYP3A4 (0.36) TSHRCYP3A4ALDH1A1HSD17B10HPGD
SCHEMBL29539 0.77
SCHEMBL20528826 0.75 TRPA1 (0.34) TSHRPARP1
SCHEMBL8343541 0.75 TRPA1 (0.34) TSHRPARP1
SCHEMBL6917860 0.72 CYP3A4 (0.38) TSHRCYP3A4ALDH1A1HSD17B10HPGD
SCHEMBL7335527 0.70 MAOA (0.34) ALDH1A1HPGDKDM4ELMNA
SCHEMBL1005829 0.69 ALDH1A1 (0.45) TSHRCYP3A4ALDH1A1HSD17B10HPGD
SCHEMBL37944 0.68 TSHR (0.46) TSHRCYP3A4ALDH1A1HSD17B10HPGD
SCHEMBL28816165 0.67 TSHR (0.44) TSHRCYP3A4ALDH1A1HSD17B10HPGD
SCHEMBL27735867 0.67 TSHR (0.44) TSHRCYP3A4ALDH1A1HSD17B10HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111527094-B Compound, polymer compound, material for organic element, organic electroluminescent element, display device, and lighting device 学校法人关西学院 2024-03-26 CN disclosed
US-11807656-B2 Polycyclic aromatic compound and light emission layer-forming composition KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2023-11-07 US disclosed
CN-111212844-B Dimer compound, material for organic element, organic electroluminescent element, display device, and lighting device 学校法人关西学院 2023-08-25 CN disclosed
US-11653565-B2 Polycyclic aromatic compound KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2023-05-16 US disclosed
US-11637250-B2 Polycyclic aromatic compound and light emitting layer-forming composition KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2023-04-25 US disclosed
US-11539003-B2 Polycyclic aromatic amino compound KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2022-12-27 US disclosed
CN-109863155-B Polycyclic aromatic compound, material for organic element, organic electroluminescent element, display device, and lighting device 学校法人关西学院 2022-09-13 CN disclosed
CN-110049990-B Polycyclic aromatic amino compound, material for organic element, organic electroluminescent element, display device, and lighting device 学校法人关西学院 2022-09-13 CN disclosed
US-11407774-B2 Polycyclic aromatic compound KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2022-08-09 US disclosed
US-11342511-B2 Azoline ring-containing compound, electron transport/injection layer material containing the same, and organic electroluminescent element using the same SK MATERIALS JNC CO., LTD. (KR) 2022-05-24 US disclosed
US-20150236274-A1 POLYCYCLIC AROMATIC COMPOUND KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2015-08-20 US disclosed
EP-2897184-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE, AND LIGHTING DEVICE JNC Corporation (JP) 2015-07-22 EP disclosed
US-9070885-B2 Anthracene compound and organic electroluminescence element using same JNC CORPORATION (JP) 2015-06-30 US disclosed
US-20150097162-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE, AND LIGHTING DEVICE JNC CORPORATION (JP) 2015-04-09 US disclosed
US-20140319510-A1 BENZOFLUORENE COMPOUND, MATERIAL FOR LUMINESCENT LAYER USING SAID COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE JNC CORPORATION (JP) 2014-10-30 US disclosed
EP-2784057-A1 BENZOFLUORENE COMPOUND, MATERIAL FOR LUMINESCENT LAYER USING SAID COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE JNC Corporation (JP) 2014-10-01 EP disclosed
EP-2669262-A1 NOVEL ANTHRACENE COMPOUND AND ORGANIC ELECTROLUMINESCENCE ELEMENT USING SAME JNC Corporation (JP) 2013-12-04 EP disclosed
US-20130292665-A1 NOVEL ANTHRACENE COMPOUND AND ORGANIC ELECTROLUMINESCENCE ELEMENT USING SAME JNC CORPORATION (JP) 2013-11-07 US disclosed
CN-103328420-A Novel anthracene compound and organic electroluminescence element using same JNC CORP 2013-09-25 CN disclosed
US-20100298530-A1 Photoresponsive Base Having Triazole Skeleton TOPPAN PRINTING CO., LTD. (JP) 2010-11-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11539003-B2 Polycyclic aromatic amino compound BCAT2, BCAT1, SLC7A5 TSHR 4324/4885CYP3A4 2540/4885ALDH1A1 3738/4885
US-11807656-B2 Polycyclic aromatic compound and light emission layer-forming composition ARNT, TYR, NLRP3 TSHR 4586/4885CYP3A4 271/4885ALDH1A1 2119/4885
US-20150236274-A1 POLYCYCLIC AROMATIC COMPOUND PAH, ALK, AOC2 TSHR 4594/4885CYP3A4 1205/4885ALDH1A1 3052/4885
US-11653565-B2 Polycyclic aromatic compound ETV6, EBPL, EML4 TSHR 4531/4885CYP3A4 2378/4885ALDH1A1 3566/4885
US-11342511-B2 Azoline ring-containing compound, electron transport/injection layer material containing the same, and organic electroluminescent element using the same SLC7A5, EML4, ARNT TSHR 4029/4885CYP3A4 301/4885ALDH1A1 1266/4885
US-11637250-B2 Polycyclic aromatic compound and light emitting layer-forming composition C9, TYR, CCNA1 TSHR 4846/4885CYP3A4 637/4885ALDH1A1 990/4885
US-11407774-B2 Polycyclic aromatic compound ETV6, EML4, EBPL TSHR 4526/4885CYP3A4 2302/4885ALDH1A1 3563/4885
US-20100298530-A1 Photoresponsive Base Having Triazole Skeleton POLL, POLR2E, LIG4 TSHR 852/4885CYP3A4 1128/4885ALDH1A1 832/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.