Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | EDNRA | P25101 | 1/20 | 0.34 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30681723 | 1.00 | KMT2A (0.45) | KMT2AKEAP1NFE2L2TRPA1ATM | |
| SCHEMBL8663359 | 0.89 | ALDH1A1 (0.57) | KMT2AKEAP1NFE2L2TSHRSMN1; SMN2 | |
| SCHEMBL11348878 | 0.88 | ALDH1A1 (0.40) | KMT2AKEAP1NFE2L2TSHRALDH1A1 | |
| SCHEMBL7370782 | 0.82 | CA12 (0.40) | KMT2AKEAP1NFE2L2SMN1; SMN2ALDH1A1 | |
| SCHEMBL1423331 | 0.82 | KDM4E (0.43) | KMT2AALDH1A1NPSR1MAPTRXFP1 | |
| SCHEMBL4439 | 0.81 | ALDH1A1 (0.44) | KMT2AKEAP1NFE2L2TSHRALDH1A1 | |
| SCHEMBL1538438 | 0.81 | KMT2A (0.56) | KMT2AKEAP1NFE2L2TRPA1ATM | |
| SCHEMBL30950298 | 0.81 | ALDH1A1 (0.44) | KMT2AKEAP1NFE2L2TSHRALDH1A1 | |
| SCHEMBL7896751 | 0.81 | KMT2A (0.47) | KMT2AKEAP1NFE2L2TRPA1ATM | |
| SCHEMBL5446748 | 0.80 | KEAP1 (0.56) | KMT2AKEAP1NFE2L2TRPA1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 181 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111244296-B | Quantum dot light-emitting diode and preparation method thereof | TCL科技集团股份有限公司 | 2021-05-18 | — | — | CN | claimed |
| CN-111234802-A | Preparation method of quantum dots | TCL集团股份有限公司 | 2020-06-05 | — | — | CN | claimed |
| CN-111244296-A | Quantum dot light-emitting diode and preparation method thereof | TCL集团股份有限公司 | 2020-06-05 | — | — | CN | claimed |
| CN-111234804-A | Preparation method of quantum dots | TCL集团股份有限公司 | 2020-06-05 | — | — | CN | claimed |
| CN-102746233-A | Process for the sulfinylation of a pyrazole derivative | BASF SE | 2012-10-24 | — | — | CN | claimed |
| CN-102746234-A | Process for the sulfinylation of a pyrazole derivative | BASF SE | 2012-10-24 | — | — | CN | claimed |
| CN-101589027-A | Process for the sulfinylation of a pyrazole derivative | BASF SE (DE) | 2009-11-25 | — | — | CN | claimed |
| CN-101583602-A | Process for the sulfinylation of pyrazole derivatives | BASF SE (DE) | 2009-11-18 | — | — | CN | claimed |
| CN-101578270-A | Process for the sulfinylation of pyrazole derivatives | BASF SE (DE) | 2009-11-11 | — | — | CN | claimed |
| US-12479842-B2 | Pyrido[3,2-d]pyrimidine compounds uses thereof for treating a proliferative disease | UNIVERSITE DE MONTREAL (CA) | 2025-11-25 | — | — | US | disclosed |
| US-20250270207-A1 | PYRIDO[3,2-D]PYRIMIDINE COMPOUNDS USES THEREOF FOR TREATING A PROLIFERATIVE DISEASE | UNIVERSITE DE MONTREAL (CA) | 2025-08-28 | — | — | US | disclosed |
| US-20240399776-A1 | COLOR DEVELOPER, THERMAL RECORDING MATERIAL, AND THERMAL RECORDING LAYER COATING MATERIAL | SANKO CO., LTD. (JP) | 2024-12-05 | — | — | US | disclosed |
| US-12139488-B2 | Pyrido[3,2-d]pyrimidine compounds uses thereof for treating a proliferative disease | Université de Montréal (CA) | 2024-11-12 | — | — | US | disclosed |
| US-20240317747-A1 | PYRIDO[3,2-D]PYRIMIDINE COMPOUNDS USES THEREOF FOR TREATING A PROLIFERATIVE DISEASE | Université de Montréal (CA) | 2024-09-26 | — | — | US | disclosed |
| US-4041017-A | Reactive light-sensitive high polymer compound containing furyl pentadienic ester groups and insolubilized by action of heat, light or electron beams | FUJI PHOTO FILM CO., LTD. (JA) | 1977-08-09 | — | — | US | disclosed |
| US-4002679-A | Preparation of polybenzimidazoles | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 1977-01-11 | — | — | US | disclosed |
| US-4001268-A | SUBSTITUTED PHENYL-BENZIMIDAZO COMPOUNDS | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 1977-01-04 | — | — | US | disclosed |
| US-3963763-A | Anthraquinone dyestuffs | BAYER AKTIENGESELLSCHAFT (DT) | 1976-06-15 | — | — | US | disclosed |
| US-3932419-A | QUINOLINE DYES | BAYER AKTIENGESELLSCHAFT (DT) | 1976-01-13 | — | — | US | disclosed |
| US-3931248-A | Reactive high polymer compound | FUJI PHOTO FILM CO., LTD. (JA) | 1976-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250270207-A1 | PYRIDO[3,2-D]PYRIMIDINE COMPOUNDS USES THEREOF FOR TREATING A PROLIFERATIVE DISEASE | BRAF, NRAS, KRAS | KMT2A 2292/4885KEAP1 2800/4885NFE2L2 2895/4885 |
| US-20240317747-A1 | PYRIDO[3,2-D]PYRIMIDINE COMPOUNDS USES THEREOF FOR TREATING A PROLIFERATIVE DISEASE | BRAF, NRAS, KRAS | KMT2A 2292/4885KEAP1 2800/4885NFE2L2 2895/4885 |
| US-12139488-B2 | Pyrido[3,2-d]pyrimidine compounds uses thereof for treating a proliferative disease | BRAF, NRAS, KRAS | KMT2A 2292/4885KEAP1 2800/4885NFE2L2 2895/4885 |
| US-12479842-B2 | Pyrido[3,2-d]pyrimidine compounds uses thereof for treating a proliferative disease | BRAF, NRAS, DPYD | KMT2A 2305/4885KEAP1 2880/4885NFE2L2 2939/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.