Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | EDNRA | P25101 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9634830 | 0.84 | KMT2A (0.51) | KDM4EALDH1A1L3MBTL1KMT2AHSD11B1 | |
| SCHEMBL11348878 | 0.84 | ALDH1A1 (0.40) | ALDH1A1KMT2AHSD11B1CYP3A4MCOLN3 | |
| SCHEMBL30681723 | 0.82 | KMT2A (0.45) | ALDH1A1L3MBTL1KMT2AHSD11B1MAPT | |
| SCHEMBL691798 | 0.82 | KMT2A (0.45) | ALDH1A1L3MBTL1KMT2AHSD11B1MAPT | |
| SCHEMBL4439 | 0.82 | ALDH1A1 (0.44) | KDM4EALDH1A1L3MBTL1KMT2AHSD11B1 | |
| SCHEMBL30950298 | 0.82 | ALDH1A1 (0.44) | KDM4EALDH1A1L3MBTL1KMT2AHSD11B1 | |
| SCHEMBL475089 | 0.82 | ALDH1A1 (0.55) | KDM4EALDH1A1L3MBTL1KMT2AHSD11B1 | |
| SCHEMBL29468592 | 0.82 | ALDH1A1 (0.55) | KDM4EALDH1A1L3MBTL1KMT2AHSD11B1 | |
| SCHEMBL4618048 | 0.81 | HTR6 (0.49) | KDM4EALDH1A1KMT2AHSD11B1MAPT | |
| Water SCHEMBL9476427 | 0.80 | ALDH1A1 (0.42) | KDM4EALDH1A1L3MBTL1KMT2AHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2102214-B1 | 4, 5, 6, 7-TETRAHYDRO-THIENO [3, 2-C] PYRIDINE DERIVATIVES AS H3 MODULATORS | HOFFMANN LA ROCHE (CH) | 2011-03-23 | — | — | EP | disclosed |