Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | NAAA | Q02083 | 2/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PPM1B | O75688 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.33 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27414978 | 0.94 | ALDH1A1 (0.54) | ALDH1A1NAAACES2CES1 | |
| SCHEMBL27497691 | 0.92 | ALDH1A1 (0.52) | ALDH1A1NAAACES2CES1MAPT | |
| SCHEMBL19555230 | 0.87 | ALDH1A1 (0.47) | ALDH1A1NLRP3 | |
| SCHEMBL28307625 | 0.85 | NAAA (0.53) | ALDH1A1NAAACES2CES1MAPT | |
| SCHEMBL28919745 | 0.84 | NAAA (0.56) | NAAACES2CES1MAPTTSHR | |
| SCHEMBL2987771 | 0.83 | MAPT (0.37) | ALDH1A1NAAAMAPTPPM1BPTPN1 | |
| SCHEMBL15824301 | 0.79 | NAAA (0.58) | ALDH1A1NAAAMAPT | |
| SCHEMBL10798834 | 0.77 | LMNA (0.46) | ALDH1A1TSHR | |
| SCHEMBL776049 | 0.77 | ALDH1A1 (0.43) | ALDH1A1NAAACES2CES1 | |
| SCHEMBL30568759 | 0.77 | ALDH1A1 (1.00) | ALDH1A1NAAACES2CES1FFAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004079334-A2 | BIOMARKER DETECTION BASED ON ASPECTS OF ION MOBILITY | SIONEX CORPORATION (US) | 2004-09-16 | — | — | WO | disclosed |
| US-6623928-B2 | Determining the sequence of a nucleic acid; obtain sample, incubate with labeled probe, separate labeled nucleotide sequences, remove label, detect labels | QIAGEN GENOMICS, INC. | 2003-09-23 | — | — | US | disclosed |
| US-20020119456-A1 | Methods and compositions for determining the sequence of nucleic acid molecules | AGILENT TECHNOLOGIES, INC. | 2002-08-29 | — | — | US | disclosed |
| US-5164506-A | Substituted 2-pyridones and pyrid-2-thiones compounds | BAYER AKTIENGESELLSCHAFT (DE) | 1992-11-17 | — | — | US | disclosed |
| US-5032602-A | Inhibiting HMG-CoA reductase with novel substituted 2-pyridones and pyrid-2-thiones | BAYER AKTIENGESELLSCHAFT (DE) | 1991-07-16 | — | — | US | disclosed |
| CN-1034716-A | Disubstituted pyridines and preparation method thereof | BAYER AG (DE) | 1989-08-16 | — | — | CN | disclosed |
| US-4229469-A | Insecticidal alkadienylcyclopropanecarboxylates | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1980-10-21 | — | — | US | disclosed |