Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 3-Methylbutanol SCHEMBL2815147 | 0.97 | SMN1; SMN2 (0.53) | LMNAALDH1A1TSHRMEN1KMT2A | |
| 1-Hexanol SCHEMBL5665303 | 0.95 | LMNA (0.65) | LMNAALDH1A1TSHRMEN1KMT2A | |
| 1-Hexanol SCHEMBL11567395 | 0.95 | LMNA (0.65) | LMNAALDH1A1TSHRMEN1KMT2A | |
| Cetostearyl Alcohol SCHEMBL27309095 | 0.95 | LMNA (0.65) | LMNAALDH1A1TSHRMEN1KMT2A | |
| 3-Methylbutanol SCHEMBL28101626 | 0.92 | SMN1; SMN2 (0.48) | LMNAALDH1A1TSHRMEN1KMT2A | |
| 3-Methylbutanol SCHEMBL2354231 | 0.92 | SMN1; SMN2 (0.63) | LMNAALDH1A1TSHRMEN1KMT2A | |
| Octanol SCHEMBL27781403 | 0.91 | LMNA (0.59) | LMNAALDH1A1TSHRMEN1KMT2A | |
| 3-Methylbutanol SCHEMBL28244429 | 0.90 | SMN1; SMN2 (0.46) | LMNAALDH1A1TSHRMEN1KMT2A | |
| 3-Methylbutanol SCHEMBL2558666 | 0.89 | ALDH1A1 (0.61) | LMNAALDH1A1TSHRMEN1KMT2A | |
| 2-Heptanol SCHEMBL29044242 | 0.85 | OPRM1 (0.46) | LMNAALDH1A1TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112305135-B | Thilidazine detection method | 北京和合医学诊断技术股份有限公司 | 2022-08-12 | — | — | CN | disclosed |
| CN-112305135-A | Thilidazine detection method | 北京和合医学诊断技术股份有限公司 | 2021-02-02 | — | — | CN | disclosed |
| EP-0629132-B1 | PURIFIED VACUOLATING TOXIN FROM HELICOBACTER PYLORI AND METHODS TO USE SAME | UNIV VANDERBILT (US) | 2004-08-11 | — | — | EP | disclosed |
| EP-0641440-B1 | REAGENTS AND METHODS FOR THE QUANTIFICATION OF TOTAL DOXEPINS IN BIOLOGICAL FLUIDS | ABBOTT LAB (US) | 2000-11-08 | — | — | EP | disclosed |
| US-5859219-A | ISOLATED NUCLEOTIDE SEQUENCES USED FOR DETECTION OF INFECTION AS PRIMERS FOR AMPLIFICATION AND PROBES FOR HYBRIDIZATION; ANTIULCER AGENTS; ANTICANCER AGENTS | VANDERBILT UNIVERSITY (US) | 1999-01-12 | — | — | US | disclosed |
| EP-0629132-A4 | PURIFIED VACUOLATING TOXIN FROM -i(HELICOBACTER) PYLORI AND METHODS TO USE SAME. | UNIV VANDERBILT (US) | 1997-02-26 | — | — | EP | disclosed |
| EP-0641440-A4 | REAGENTS AND METHODS FOR THE QUANTIFICATION OF TOTAL DOXEPINS IN BIOLOGICAL FLUIDS. | ABBOTT LAB (US) | 1996-04-10 | — | — | EP | disclosed |
| US-5464767-A | Reagents and methods for the quantification of total doxepins in biological fluids | ABBOTT LABORATORIES (US) | 1995-11-07 | — | — | US | disclosed |
| EP-0641440-A1 | REAGENTS AND METHODS FOR THE QUANTIFICATION OF TOTAL DOXEPINS IN BIOLOGICAL FLUIDS | ABBOTT LABORATORIES (US) | 1995-03-08 | — | — | EP | disclosed |
| EP-0629132-A1 | PURIFIED VACUOLATING TOXIN FROM $i(HELICOBACTER) PYLORI AND METHODS TO USE SAME | VANDERBILT UNIVERSITY (US) | 1994-12-21 | — | — | EP | disclosed |
| US-5332661-A | Reagents and methods for the quantification of total doxepins in biological fluids | ABBOTT LABORATORIES (US) | 1994-07-26 | — | — | US | disclosed |
| WO-1993016723-A1 | PURIFIED VACUOLATING TOXIN FROM HELICOBACTER PYLORI AND METHODS TO USE SAME | VANDERBILT UNIVERSITY (US) | 1993-09-02 | — | — | WO | disclosed |
| WO-1993003372-A1 | REAGENTS AND METHODS FOR THE QUANTIFICATION OF TOTAL DOXEPINS IN BIOLOGICAL FLUIDS | ABBOTT LABORATORIES (US) | 1993-02-18 | — | — | WO | disclosed |