Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GJB2 | P29033 | 4/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | FGF1 | P05230 | 3/20 | 0.33 |
| ▸ | FGF2 | P09038 | 3/20 | 0.33 |
| ▸ | VEGFA | P15692 | 3/20 | 0.33 |
| ▸ | HPSE | Q9Y251 | 3/20 | 0.33 |
| ▸ | GBA1 | P04062 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TNF | P01375 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6918062 | 1.00 | GJB2 (0.36) | GJB2MAPK1FGF1FGF2VEGFA | |
| SCHEMBL6919660 | 1.00 | GJB2 (0.36) | GJB2MAPK1FGF1FGF2VEGFA | |
| SCHEMBL6919792 | 0.94 | GJB2 (0.33) | GJB2MAPK1MEN1KMT2ACA2 | |
| SCHEMBL9157000 | 0.86 | MAPK1 (0.47) | GJB2MAPK1FGF1FGF2VEGFA | |
| SCHEMBL9153757 | 0.86 | MAPK1 (0.47) | GJB2MAPK1FGF1FGF2VEGFA | |
| SCHEMBL6265327 | 0.78 | LMNA (0.34) | MAPK1GBA1MEN1KMT2ALMNA | |
| SCHEMBL6813908 | 0.78 | LMNA (0.34) | MAPK1GBA1MEN1KMT2ALMNA | |
| SCHEMBL6814043 | 0.78 | LMNA (0.34) | MAPK1GBA1MEN1KMT2ALMNA | |
| SCHEMBL6265348 | 0.78 | LMNA (0.34) | MAPK1GBA1MEN1KMT2ALMNA | |
| SCHEMBL6814750 | 0.78 | LMNA (0.34) | MAPK1GBA1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1144425-B1 | DERIVATIVES OF MONOSACCHARIDES AS CELL ADHESION INHIBITORS | RANBAXY LAB LTD (IN) | 2004-06-16 | — | — | EP | disclosed |
| US-6329344-B1 | UREA DERIVATIVE OF ALKYLENE DIOXYFURAN ETHERS | RANBAXY LABORATORIES LIMITED (IN) | 2001-12-11 | — | — | US | disclosed |