Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | GJB2 | P29033 | 1/20 | 0.36 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.35 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.35 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | FGF1 | P05230 | 3/20 | 0.33 |
| ▸ | FGF2 | P09038 | 3/20 | 0.33 |
| ▸ | VEGFA | P15692 | 3/20 | 0.33 |
| ▸ | HPSE | Q9Y251 | 3/20 | 0.33 |
| ▸ | TNF | P01375 | 1/20 | 0.33 |
| ▸ | CETP | P11597 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9157000 | 1.00 | MAPK1 (0.47) | MAPK1GJB2GBA1LGALS8LGALS3 | |
| SCHEMBL28294670 | 0.91 | MAPK1 (0.50) | MAPK1GJB2GBA1LGALS8LGALS3 | |
| SCHEMBL28296334 | 0.91 | MAPK1 (0.50) | MAPK1GJB2GBA1LGALS8LGALS3 | |
| SCHEMBL6919660 | 0.86 | GJB2 (0.36) | MAPK1GJB2GBA1LMNAMEN1 | |
| SCHEMBL6918658 | 0.86 | GJB2 (0.36) | MAPK1GJB2GBA1LMNAMEN1 | |
| SCHEMBL6918062 | 0.86 | GJB2 (0.36) | MAPK1GJB2GBA1LMNAMEN1 | |
| SCHEMBL8578439 | 0.82 | LGALS8 (0.56) | MAPK1GJB2GBA1LGALS8LGALS3 | |
| SCHEMBL812311 | 0.82 | PI4KA (0.34) | MAPK1LMNA | |
| SCHEMBL29291459 | 0.80 | MAPK1 (0.57) | MAPK1GJB2GBA1LGALS8LGALS3 | |
| SCHEMBL6270119 | 0.80 | LMNA (0.48) | MAPK1GBA1LMNACYP1A2THPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5432163-A | Anti-proliferative and anti-inflammatory compounds: derivatives of pentose monosaccharides | GREENWICH PHARMACEUTICALS INCORPORATED (US) | 1995-07-11 | — | — | US | disclosed |