Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 17/20 | 0.52 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | MASP2 | O00187 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6918723 | 1.00 | F2 (0.52) | F2PRSS1CYP3A4MASP2CTSL | |
| SCHEMBL6919843 | 0.91 | F2 (0.53) | F2PRSS1 | |
| SCHEMBL6078552 | 0.86 | F2 (0.69) | F2PRSS1 | |
| SCHEMBL6079196 | 0.75 | F2 (0.69) | F2PRSS1CYP3A4 | |
| SCHEMBL6918158 | 0.74 | ALDH1A1 (0.49) | F2PRSS1CYP3A4CTSLCTSS | |
| SCHEMBL6919374 | 0.72 | CYP3A4 (0.54) | F2PRSS1CYP3A4 | |
| SCHEMBL6919370 | 0.72 | CYP3A4 (0.54) | F2PRSS1CYP3A4 | |
| SCHEMBL6919773 | 0.72 | F2 (0.40) | F2PRSS1CYP3A4CTSLCTSS | |
| SCHEMBL6921244 | 0.71 | F2 (0.47) | F2PRSS1CYP3A4 | |
| SCHEMBL6919204 | 0.70 | F2 (0.48) | F2PRSS1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004032834-A2 | THROMBIN INHIBITORS | MERCK & CO., INC. (US) | 2004-04-22 | — | — | WO | disclosed |