SCHEMBL6918933

SCHEMBL6918933

Cl[Hf](Cl)(C1C=Cc2ccccc21)C1c2ccccc2-c2ccccc21

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 1/20 0.32
HTR2A P28223 1/20 0.32
CYP2D6 P10635 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL819247 0.85 HTR6 (0.41) HTR6HTR2ACYP2D6
Ethylene SCHEMBL9289285 0.82 HTR6 (0.39) HTR6HTR2A
SCHEMBL3385243 0.77 HTR2A (0.38) HTR6HTR2ACYP2D6
SCHEMBL6914252 0.76
SCHEMBL7066600 0.76 GPR3 (0.31) HTR2ACYP2D6
SCHEMBL7063940 0.76 HTR6 (0.33) HTR6HTR2ACYP2D6
Hydrochloric Acid SCHEMBL6916190 0.75
Hydrochloric Acid SCHEMBL7066993 0.74 KDM4E (0.32)
SCHEMBL5395321 0.74
SCHEMBL5601006 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0927201-B1 CATALYST SYSTEM FOR (CO)POLYMERIZATION OF OLEFINS AND PROCESS FOR THE PREPARATION OF OLEFIN (CO)POLYMERS USING THE CATALYST SYSTEM HYUNDAI PETROCHEMICAL CO LTD (KR) 2004-04-14 EP disclosed
US-5646083-A Process for the preparation of a bridged metallocene compound as well as a catalyst component and a process for the polymerization of olefins DSM N.V. (NL) 1997-07-08 US disclosed