Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 3/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | CA4 | P22748 | 3/20 | 0.37 |
| ▸ | CA7 | P43166 | 3/20 | 0.37 |
| ▸ | CA9 | Q16790 | 3/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA6 | P23280 | 2/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MASP2 | O00187 | 1/20 | 0.37 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6207088 | 0.86 | ALOX5 (0.47) | ALDH1A1MAPK1ALOX5KDM4EMAPT | |
| SCHEMBL19859433 | 0.85 | TSHR (0.45) | ALDH1A1KDM4ETSHRSIRT2HSD17B10 | |
| SCHEMBL18522671 | 0.74 | TSHR (0.46) | ALDH1A1MAPK1ALOX5KDM4EMAPT | |
| SCHEMBL9309297 | 0.74 | ALDH1A1 (0.57) | ALDH1A1MAPK1ALOX5KDM4EMAPT | |
| SCHEMBL18128163 | 0.72 | TSHR (0.46) | ALDH1A1ALOX5KDM4ETSHRHSD17B10 | |
| SCHEMBL3275976 | 0.71 | ALDH1A1 (0.36) | ALDH1A1KDM4ECA12CA2CA7 | |
| SCHEMBL28406723 | 0.71 | ALOX5 (0.67) | ALDH1A1MAPK1ALOX5KDM4EMAPT | |
| SCHEMBL3914969 | 0.67 | KDM4E (0.42) | ALDH1A1ALOX5KDM4EMAPTCA12 | |
| SCHEMBL8751791 | 0.67 | SNCA (0.41) | ALDH1A1MAPK1KDM4EMAPTCA12 | |
| SCHEMBL3732847 | 0.67 | ALDH1A1 (0.53) | ALDH1A1MAPK1ALOX5KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3873896-A1 | TRICYCLIC COMPOUNDS AS STING AGONISTS, AND PREPARATION METHODS AND MEDICINAL USES THEREOF | Jiangsu Hengrui Medicine Co., Ltd. (CN) | 2021-09-08 | — | — | EP | disclosed |
| WO-2020124059-A1 | TRICYCLIC COMPOUNDS AS STING AGONISTS, AND PREPARATION METHODS AND MEDICINAL USES THEREOF | Eternity Bioscience Inc. (US) | 2020-06-18 | — | — | WO | disclosed |
| WO-2004014389-A1 | 3,4-DIHYDROQUINOLIN-2-ONE, 5,6-FUSED OXAZIN-3-ONE, AND 5,6-FUSED THIAZIN-3-ONE DERIVATIVES AS MATRIX METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2004-02-19 | — | — | WO | disclosed |
| EP-0651753-A1 | PYRIDONECARBOXYLIC ACID DERIVATIVES AND PROCESSES FOR PREPARING THE SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1995-05-10 | — | — | EP | disclosed |
| EP-0197807-A1 | Pyrazolobenzoxazine derivatives, their salts, process and preparation intermediates, use as medicaments and compositions containing them | ROUSSEL-UCLAF (FR) | 1986-10-15 | — | — | EP | disclosed |