Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.43 |
| ▸ | F9 | P00740 | 2/20 | 0.43 |
| ▸ | F10 | P00742 | 2/20 | 0.43 |
| ▸ | PLG | P00747 | 2/20 | 0.43 |
| ▸ | PLAU | P00749 | 2/20 | 0.43 |
| ▸ | PLAT | P00750 | 2/20 | 0.43 |
| ▸ | F11 | P03951 | 2/20 | 0.43 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.43 |
| ▸ | F7 | P08709 | 2/20 | 0.43 |
| ▸ | CFD | P00746 | 1/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 6/20 | 0.39 |
| ▸ | PTGDR | Q13258 | 5/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28228801 | 0.80 | CNR2 (0.44) | PTGER4PTGDRPTGER2USP2MAPK1 | |
| SCHEMBL1078697 | 0.77 | KDM4E (0.38) | PTGER4PTGDRHTR2AHTR2CNR4A2 | |
| SCHEMBL1271088 | 0.75 | PTGER4 (0.54) | PTGER4PTGDRPTGER2NOTUMTBXA2R | |
| SCHEMBL12932033 | 0.74 | FABP4 (0.54) | PTGER4PTGER2USP2MAPK1HSD17B10 | |
| SCHEMBL9236518 | 0.74 | NR4A1 (0.40) | F2F9F10PLGPLAU | |
| SCHEMBL7652408 | 0.74 | NOTUM (0.56) | PTGER4PTGDRPTGER2NOTUMTBXA2R | |
| SCHEMBL13557126 | 0.73 | MAPK1 (0.43) | PTGER4PTGDRNR4A1NR4A2NR4A3 | |
| SCHEMBL7428564 | 0.73 | NPC1 (0.39) | F2F9F10PLGPLAU | |
| SCHEMBL12900285 | 0.73 | PTGER4 (0.67) | PTGER4PTGDRPTGER2PTGER3 | |
| SCHEMBL7679127 | 0.72 | KMT2A (0.41) | F2F9F10PLGPLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011008572-A2 | 5-HT3 RECEPTOR MODULATORS, METHODS OF MAKING, AND USE THEREOF | ALBANY MOLECULAR RESEARCH, INC. (US) | 2011-01-20 | — | — | WO | disclosed |