Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 7/20 | 0.39 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | BAD | Q92934 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 6/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.37 |
| ▸ | PTGDR | Q13258 | 3/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.37 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.37 |
| ▸ | PTGFR | P43088 | 1/20 | 0.37 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.37 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9236518 | 0.86 | NR4A1 (0.40) | KMT2ANR4A1NR4A2NR4A3MCL1 | |
| SCHEMBL22800155 | 0.81 | MAPT (0.38) | KMT2ANR4A1NR4A2NR4A3MCL1 | |
| SCHEMBL7686232 | 0.81 | TSHR (0.46) | KMT2ANPC1RAB9AMEN1HSD17B10 | |
| SCHEMBL25282089 | 0.77 | KMT2A (0.45) | KMT2ANPC1NR4A1NR4A2NR4A3 | |
| SCHEMBL7652408 | 0.77 | NOTUM (0.56) | PTGER4PTGDRTBXA2RPTGER1PTGFR | |
| SCHEMBL1395936 | 0.74 | ALDH1A1 (0.37) | KMT2AMEN1ALDH1A1POLB | |
| SCHEMBL25010273 | 0.74 | ADRA2A (0.46) | KMT2ANPC1RAB9A | |
| SCHEMBL987890 | 0.74 | PTGER4 (0.51) | PTGER4PTGDRTBXA2RPTGER1PTGFR | |
| SCHEMBL13557126 | 0.74 | MAPK1 (0.43) | KMT2ANPC1NR4A1NR4A2NR4A3 | |
| SCHEMBL5056802 | 0.73 | NPC1 (0.60) | KMT2ANPC1RAB9AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6362201-B1 | ANTIINFLAMMATORY AGENTS; ANTIALLERGENS | MERCK & CO., INC. | 2002-03-26 | — | — | US | disclosed |