Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 4/20 | 0.53 |
| ▸ | PTGER4 | P35408 | 4/20 | 0.53 |
| ▸ | PTGER3 | P43115 | 4/20 | 0.53 |
| ▸ | PTGER2 | P43116 | 4/20 | 0.53 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | TNF | P01375 | 1/20 | 0.40 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.40 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TSPO | P30536 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31357767 | 0.81 | PTGER1 (0.48) | PTGER1PTGER4PTGER3PTGER2MAOB | |
| SCHEMBL3653914 | 0.79 | PTGER1 (0.45) | PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL28366425 | 0.78 | PTGER1 (0.44) | PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL6919116 | 0.77 | AR (0.47) | PTGER1PTGER4PTGER3PTGER2MAOB | |
| SCHEMBL29172711 | 0.77 | L3MBTL1 (0.45) | PTGER1PTGER4PTGER3PTGER2MGLL | |
| SCHEMBL27145050 | 0.77 | PTGER1 (0.43) | PTGER1PTGER4PTGER3PTGER2 | |
| Water SCHEMBL2340363 | 0.77 | MRGPRX4 (0.50) | PTGER1PTGER4PTGER3PTGER2MAOB | |
| SCHEMBL23210272 | 0.77 | PTGER1 (0.45) | PTGER1PTGER4PTGER3PTGER2MAOB | |
| SCHEMBL31357736 | 0.77 | PTGER1 (0.47) | PTGER1PTGER4PTGER3PTGER2MGLL | |
| SCHEMBL31357663 | 0.77 | PTGER1 (0.47) | PTGER1PTGER4PTGER3PTGER2MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040132789-A1 | Antioxidant and radical scavenging activity of synthetic analogs of desferrithiocin | UNIVERSITY OF FLORIDA | 2004-07-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040132789-A1 | Antioxidant and radical scavenging activity of synthetic analogs of desferrithiocin | TXNRD2, SOD1, PRDX3 | PTGER1 2061/4885PTGER4 1206/4885PTGER3 2271/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.