Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.47 |
| ▸ | PIR | O00625 | 1/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.44 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.44 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP7 | P09237 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP12 | P39900 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10537261 | 0.86 | AR (0.47) | ARPIRPTGER1PTGER4PTGER3 | |
| SCHEMBL7371569 | 0.84 | AR (0.56) | ARPIRMGLLCA12CA1 | |
| SCHEMBL9117894 | 0.82 | HTR1A (0.52) | ARPIRPTGER1PTGER4PTGER3 | |
| SCHEMBL31662455 | 0.81 | SCN9A (0.45) | ARPIRMGLLCA12CA1 | |
| SCHEMBL7402194 | 0.80 | MGLL (0.56) | ARPIRMGLLCA12CA1 | |
| SCHEMBL10983891 | 0.79 | AR (0.58) | ARPIRMGLLCA12CA1 | |
| SCHEMBL10460127 | 0.79 | PTGER1 (0.42) | ARPTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL9837799 | 0.78 | SLC2A1 (0.42) | ARPIRPTGER1PTGER4PTGER3 | |
| SCHEMBL6919113 | 0.77 | PTGER1 (0.53) | ARPTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL7028389 | 0.77 | CNR2 (0.50) | CA12CA1CA9CA2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040132789-A1 | Antioxidant and radical scavenging activity of synthetic analogs of desferrithiocin | UNIVERSITY OF FLORIDA | 2004-07-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040132789-A1 | Antioxidant and radical scavenging activity of synthetic analogs of desferrithiocin | TXNRD2, SOD1, PRDX3 | AR 3752/4885PIR 284/4885PTGER1 2061/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.