Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
| ▸ | ALB | P02768 | 4/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TGM2 | P21980 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.41 |
| ▸ | ESRRG | P62508 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL402067 | 0.85 | SMN1; SMN2 (0.55) | C3AR1KMT2ASMN1; SMN2ITGB3ITGA2B | |
| SCHEMBL2248048 | 0.79 | EPHX2 (0.47) | NR1H4CA2CA1KMT2AACE | |
| SCHEMBL5273134 | 0.77 | KMT2A (0.57) | CA2CA1C3AR1KMT2AITGB3 | |
| SCHEMBL28229751 | 0.77 | KMT2A (0.57) | CA2CA1C3AR1KMT2AITGB3 | |
| SCHEMBL4925425 | 0.76 | ALB (0.50) | ALBSMN1; SMN2NOD1 | |
| SCHEMBL4925430 | 0.76 | ALB (0.50) | ALBSMN1; SMN2NOD1 | |
| SCHEMBL7602117 | 0.76 | ALB (0.53) | ALBL3MBTL1ITGB3ITGA2B | |
| SCHEMBL7045847 | 0.76 | NOD1 (0.56) | CA2CA1C3AR1KMT2ANOD1 | |
| SCHEMBL7046045 | 0.76 | NOD1 (0.60) | CA2CA1C3AR1KMT2ANOD1 | |
| SCHEMBL20100673 | 0.75 | ALB (0.47) | ALBACENOD1ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011080103-A1 | DOUBLE-ACYLATED GLP-1 DERIVATIVES | NOVO NORDISK A/S (DK) | 2011-07-07 | — | — | WO | disclosed |