Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 10/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 10/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 8/20 | 0.52 |
| ▸ | MMP7 | P09237 | 3/20 | 0.48 |
| ▸ | MMP9 | P14780 | 2/20 | 0.48 |
| ▸ | MMP1 | P03956 | 2/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | MMP3 | P08254 | 1/20 | 0.48 |
| ▸ | MMP13 | P45452 | 1/20 | 0.48 |
| ▸ | MMP10 | P09238 | 1/20 | 0.47 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.44 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.43 |
| ▸ | EEF2K | O00418 | 1/20 | 0.42 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.42 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.42 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2412670 | 0.83 | MMP7 (0.52) | HDAC3HDAC6HDAC1MMP7MMP9 | |
| SCHEMBL2413093 | 0.83 | MMP7 (0.52) | HDAC3HDAC6HDAC1MMP7MMP9 | |
| SCHEMBL2406492 | 0.78 | EEF2K (0.49) | HDAC3HDAC6MMP7MMP9MMP1 | |
| SCHEMBL2409731 | 0.77 | HDAC8 (0.47) | HDAC3HDAC6HDAC1MMP7MMP9 | |
| SCHEMBL2409311 | 0.77 | MMP7 (0.54) | HDAC3HDAC6HDAC1MMP7MMP9 | |
| SCHEMBL12320083 | 0.76 | MMP7 (0.48) | HDAC3HDAC6MMP7MMP9MMP1 | |
| SCHEMBL6919174 | 0.76 | ALKBH2 (0.49) | HDAC3HDAC6HDAC1HDAC2MMP7 | |
| SCHEMBL2406751 | 0.75 | MMP7 (0.49) | HDAC3HDAC6HDAC1HDAC2MMP7 | |
| SCHEMBL15280035 | 0.73 | MMP7 (0.45) | MMP7MMP9MMP1MMP2MMP3 | |
| SCHEMBL2405981 | 0.73 | MMP1 (0.45) | HDAC3HDAC6HDAC1HDAC2MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011106632-A1 | SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2011-09-01 | — | — | WO | disclosed |