Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TDP2 | O95551 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | GALK1 | P51570 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6218240 | 0.89 | RAB9A (0.45) | SMN1; SMN2POLBL3MBTL1NPC1RAB9A | |
| SCHEMBL6921386 | 0.86 | RAB9A (0.34) | NPC1RAB9A | |
| SCHEMBL6921375 | 0.83 | HPGD (0.34) | SMN1; SMN2ALDH1A1POLBL3MBTL1KDM4E | |
| SCHEMBL6918700 | 0.80 | AKR1C3 (0.40) | POLBKDM4EPKMTSHR | |
| SCHEMBL6817245 | 0.76 | ALDH1A1 (0.39) | ALDH1A1CYP3A4POLBCYP2C19HPGD | |
| SCHEMBL6913812 | 0.76 | GPX4 (0.32) | — | |
| SCHEMBL6919351 | 0.75 | SMN1; SMN2 (0.53) | SMN1; SMN2ALDH1A1CYP3A4POLBCYP2C19 | |
| SCHEMBL6915301 | 0.72 | MAPT (0.51) | SMN1; SMN2ALDH1A1POLBCYP2C19NPC1 | |
| SCHEMBL6921135 | 0.71 | — | — | |
| SCHEMBL6820885 | 0.68 | RAB9A (0.46) | SMN1; SMN2ALDH1A1POLBL3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165505-B1 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY AND IMMUNE-SUPPRESSIVE COMPOUNDS | ABBOTT LAB (US) | 2004-09-08 | — | — | EP | claimed |