Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 3/20 | 0.71 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.66 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.66 |
| ▸ | FAAH | O00519 | 1/20 | 0.61 |
| ▸ | MGLL | Q99685 | 1/20 | 0.61 |
| ▸ | IDO1 | P14902 | 1/20 | 0.61 |
| ▸ | TDO2 | P48775 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | MGAM | O43451 | 3/20 | 0.58 |
| ▸ | AMY1A | P0DUB6 | 3/20 | 0.58 |
| ▸ | GAA | P10253 | 3/20 | 0.58 |
| ▸ | SI | P14410 | 3/20 | 0.58 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.53 |
| ▸ | MME | P08473 | 1/20 | 0.52 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7667737 | 0.85 | GRM2 (0.57) | HCAR3GRM2SLC9A1FAAHMGLL | |
| SCHEMBL6044303 | 0.83 | HCAR3 (1.00) | HCAR3GRM2SLC9A1MME | |
| SCHEMBL2734889 | 0.81 | GRM2 (1.00) | HCAR3GRM2SLC9A1RAB9ATDP1 | |
| SCHEMBL9303448 | 0.77 | PTK2 (0.72) | GRM2SLC9A1RAB9ATDP1NPC1 | |
| SCHEMBL14809085 | 0.77 | PTK2 (0.72) | GRM2SLC9A1IDO1TDO2RAB9A | |
| SCHEMBL7599503 | 0.77 | SLC9A1 (0.69) | GRM2SLC9A1IDO1TDO2RAB9A | |
| SCHEMBL6043919 | 0.77 | HCAR3 (1.00) | HCAR3GAAMMEPTK2 | |
| SCHEMBL2885662 | 0.76 | CYP11B1 (0.67) | IDO1SMN1; SMN2 | |
| SCHEMBL7594126 | 0.74 | GRM2 (0.63) | GRM2SLC9A1RAB9ATDP1NPC1 | |
| SCHEMBL12093975 | 0.74 | GAA (1.00) | RAB9AMGAMAMY1AGAASI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011021209-A1 | HISTONE DEACETYLASE INHIBITORS | PORTSMOUTH TECHNOLOGIES LLC (US) | 2011-02-24 | — | — | WO | disclosed |