Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | MDM4 | O15151 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | STK33 | Q9BYT3 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.32 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.31 |
| ▸ | AURKA | O14965 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6714034 | 0.90 | KMT2A (0.47) | MEN1KMT2AL3MBTL1KDRF10 | |
| SCHEMBL6708854 | 0.82 | KMT2A (0.42) | MEN1KMT2AHDAC1PDE10ASTK33 | |
| SCHEMBL6709991 | 0.81 | KDR (0.44) | MEN1KMT2AL3MBTL1KDRF10 | |
| SCHEMBL6711934 | 0.80 | PRSS12 (0.39) | MEN1KMT2APLA2G7NPC1RAB9A | |
| SCHEMBL6710055 | 0.80 | IRAK4 (0.41) | MEN1KMT2AHDAC1PDE10APLA2G7 | |
| SCHEMBL6713714 | 0.80 | KDR (0.43) | MEN1KMT2AL3MBTL1KDRMDM4 | |
| SCHEMBL6711406 | 0.79 | GRIK1 (0.38) | MEN1KMT2AKDM4EHDAC1PLA2G7 | |
| SCHEMBL6713406 | 0.79 | NPC1 (0.41) | PLA2G7NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6710182 | 0.78 | ALDH1A1 (0.40) | MEN1KMT2AKDM4EHDAC1PLA2G7 | |
| SCHEMBL6711762 | 0.78 | MAP3K5 (0.41) | KMT2ATP53MAPK1PLA2G7NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004018461-A2 | ANTIBACTERIAL BENZOIC ACID DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | disclosed |