Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 2/20 | 0.44 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.42 |
| ▸ | MDM4 | O15151 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | PLCG2 | P16885 | 1/20 | 0.40 |
| ▸ | STK33 | Q9BYT3 | 1/20 | 0.39 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.39 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.39 |
| ▸ | KCNE1 | P15382 | 2/20 | 0.39 |
| ▸ | KCNQ1 | P51787 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6713714 | 0.92 | KDR (0.43) | KDRGRIK1MDM4TP53MDM2 | |
| SCHEMBL6710141 | 0.91 | GRIK1 (0.44) | GRIK1PLCG2STK33NPSR1KDM4E | |
| SCHEMBL6714034 | 0.90 | KMT2A (0.47) | KDRGRIK1MDM4TP53MDM2 | |
| SCHEMBL6709929 | 0.89 | GRIK1 (0.49) | KDRGRIK1PLCG2STK33MAPT | |
| SCHEMBL6713155 | 0.88 | SERPINE1 (0.48) | GRIK1F10PLCG2STK33KMT2A | |
| SCHEMBL6709173 | 0.87 | GRIK1 (0.44) | GRIK1TP53PLCG2STK33KMT2A | |
| SCHEMBL6713656 | 0.87 | GRIK1 (0.42) | GRIK1TP53PLCG2STK33KCNQ3 | |
| SCHEMBL6708655 | 0.86 | NHERF1 (0.46) | GRIK1PLCG2STK33KMT2AMEN1 | |
| SCHEMBL6920022 | 0.86 | KDR (0.40) | KDRGRIK1MDM4TP53MDM2 | |
| SCHEMBL6707691 | 0.85 | GRIK1 (0.41) | KDRGRIK1TP53F10PLCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | KDR 3770/4885GRIK1 3885/4885MDM4 2984/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.