Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6920062 | 0.85 | ALDH1A1 (0.50) | ALDH1A1HDAC8HDAC6HDAC3HDAC4 | |
| SCHEMBL6918441 | 0.85 | ALDH1A1 (0.50) | ALDH1A1HDAC8HDAC6HDAC3HDAC4 | |
| SCHEMBL15771458 | 0.81 | ALDH1A1 (0.54) | ALDH1A1HDAC6HDAC3HDAC4HDAC1 | |
| SCHEMBL15771457 | 0.81 | ALDH1A1 (0.54) | ALDH1A1HDAC6HDAC3HDAC4HDAC1 | |
| SCHEMBL6918497 | 0.80 | HDAC6 (0.41) | HDAC8HDAC6HDAC3HDAC4HDAC1 | |
| SCHEMBL2410752 | 0.79 | HDAC6 (0.56) | ALDH1A1HDAC8HDAC6CA2HDAC3 | |
| SCHEMBL2438304 | 0.78 | MEN1 (0.55) | ALDH1A1MEN1KMT2ARCE1KDM4E | |
| SCHEMBL6919184 | 0.78 | ALDH1A1 (0.48) | ALDH1A1HDAC8HDAC6CA2HDAC3 | |
| SCHEMBL12279819 | 0.77 | ALDH1A1 (0.57) | ALDH1A1HDAC8HDAC6CA2HDAC1 | |
| SCHEMBL6918744 | 0.77 | ROCK2 (0.47) | ALDH1A1HDAC8HDAC6HDAC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011106632-A1 | SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2011-09-01 | — | — | WO | disclosed |