Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 5/20 | 0.46 |
| ▸ | HTR1A | P08908 | 3/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | UTS2R | Q9UKP6 | 4/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6824321 | 1.00 | HTR7 (0.46) | HTR7HTR1ADRD2HTR2ACNR2 | |
| SCHEMBL6826272 | 0.93 | HTR7 (0.47) | HTR7HTR1ADRD2HTR2ACNR2 | |
| SCHEMBL6378452 | 0.92 | HTR7 (0.46) | HTR7HTR1ADRD2HTR2ACNR2 | |
| SCHEMBL6823392 | 0.92 | HTR7 (0.49) | HTR7HTR1ADRD2HTR2AUTS2R | |
| SCHEMBL6820568 | 0.88 | HTR7 (0.55) | HTR7HTR1ADRD2HTR2ADRD4 | |
| SCHEMBL6823760 | 0.88 | HTR7 (0.45) | HTR7HTR1ADRD2HTR2ADRD4 | |
| SCHEMBL7348639 | 0.88 | HTR7 (0.44) | HTR7HTR1ACNR2SSTR5KCNH2 | |
| SCHEMBL6381981 | 0.85 | HTR7 (0.49) | HTR7HTR1ADRD2HTR2ASSTR5 | |
| SCHEMBL6824327 | 0.84 | HTR7 (0.42) | HTR7HTR1ADRD2HTR2ACNR2 | |
| SCHEMBL6824547 | 0.84 | HTR7 (0.42) | HTR7HTR1ADRD2HTR2ACNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004076444-A2 | NOVEL HYDROXYCOUMARANONE DERIVATIVES AS ANTITUMOR AND ANTIMETASTATIC | F. HOFFMANN-LA ROCHE AG (CH) | 2004-09-10 | — | — | WO | claimed |