SCHEMBL3084819

SCHEMBL3084819

[O-][n+]1c2ccccc2cc2ccccc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 3/20 1.00
MEN1 O00255 3/20 0.48
KMT2A Q03164 3/20 0.48
POLB P06746 1/20 0.48
CASP6 P55212 1/20 0.48
RAB9A P51151 3/20 0.45
NPC1 O15118 3/20 0.44
CRHBP P24387 1/20 0.40
CRHR2 Q13324 1/20 0.40
KEAP1 Q14145 1/20 0.40
NFE2L2 Q16236 1/20 0.40
ACHE P22303 4/20 0.38
ALDH1A1 P00352 2/20 0.38
MAPT P10636 2/20 0.38
GLA P06280 1/20 0.38
HPGD P15428 1/20 0.38
CYP2A6 P11509 1/20 0.37
ALOX12 P18054 1/20 0.37
BCHE P06276 3/20 0.33
CYP3A4 P08684 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7501877 0.83 ATM (0.69) ATMMEN1KMT2APOLBCASP6
SCHEMBL29627789 0.78 ATM (0.63) ATMMEN1KMT2APOLBCASP6
SCHEMBL6919829 0.78 ATM (0.63) ATMMEN1KMT2APOLBCASP6
SCHEMBL15780722 0.77 ATM (0.61) ATMMEN1KMT2APOLBCASP6
SCHEMBL17141397 0.77 ATM (0.61) ATMMEN1KMT2APOLBCASP6
SCHEMBL28745961 0.77 ATM (0.61) ATMMEN1KMT2APOLBCASP6
SCHEMBL244855 0.77 ATM (0.61) ATMMEN1KMT2APOLBCASP6
SCHEMBL22326431 0.77 ATM (0.61) ATMMEN1KMT2APOLBCASP6
SCHEMBL5894683 0.77 ATM (0.61) ATMMEN1KMT2APOLBCASP6
SCHEMBL10493681 0.74 ATM (0.58) ATMMEN1KMT2APOLBCASP6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103064253-B Photosensitive composition containing acridine oxide CHANGZHOU INST OF ADVANCED MATERIALS BEIJING UNIVERSITY OF CHEMICAL TECHNOLOGY 2015-04-08 CN claimed
CN-103064253-A Photosensitive composition containing acridine oxide CHANGZHOU INST OF ADVANCED MATERIALS BEIJING UNIVERSITY OF CHEMICAL TECHNOLOGY 2013-04-24 CN claimed
WO-2004052979-A1 A THERMOPLASTIC LIGHT-TRANSFORMING COPOLYMER COMPOSITION USEFUL FOR SHIFTING OF ULTRAVIOLET RADIATION INTO RED SPECTRAL REGION AND A METHOD FOR PRODUCTION THEREOF POLYMASTER LTD. (IL) 2004-06-24 WO claimed
CN-113474429-B Composition for adhesive, exterior material for electricity storage device, and method for producing same 昭和电工株式会社 2023-03-17 CN disclosed
US-9783547-B2 Water soluble 4-azapodophyllotoxin analogs CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2017-10-10 US disclosed
EP-3094622-A1 WATER SOLUBLE 4-AZAPODOPHYLLOTOXIN ANALOGS Centre National de la Recherche Scientifique (C.N.R.S.) (FR) 2016-11-23 EP disclosed
US-20160333022-A1 WATER SOLUBLE 4-AZAPODOPHYLLOTOXIN ANALOGS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2016-11-17 US disclosed
CN-106061948-A Water soluble 4-azapodophyllotoxin analogs 国家科学研究中心 2016-10-26 CN disclosed
WO-2016005979-A1 METHODS AND COMPOSITIONS FOR TREATING VIRAL INFECTIONS IN HONEYBEES THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI CENTER) (IL) 2016-01-14 WO disclosed
WO-2015107119-A1 WATER SOLUBLE 4-AZAPODOPHYLLOTOXIN ANALOGS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2015-07-23 WO disclosed
CN-103064253-B Photosensitive composition containing acridine oxide CHANGZHOU INST OF ADVANCED MATERIALS BEIJING UNIVERSITY OF CHEMICAL TECHNOLOGY 2015-04-08 CN disclosed
US-5135779-A Producing reversible redox sites on polyimide; contact with metal salts to form elemental metal; electron transfer; photoresists INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1992-08-04 US disclosed
EP-0485699-A2 Conditioning of a substrate for electroless plating thereon International Business Machines Corporation (US) 1992-05-20 EP disclosed
US-5104944-A Redox system INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1992-04-14 US disclosed
EP-0477543-A2 Method for conditioning halogenated polymeric materials and structures fabricated therewith International Business Machines Corporation (US) 1992-04-01 EP disclosed
US-5045159-A Derivatives of compounds containing a carbonyl group conjugated to an aromatic moiety and electrophilic methods of fabrication thereof INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1991-09-03 US disclosed
US-5021129-A Multilayer structures of different electroactive materials and methods of fabrication thereof INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1991-06-04 US disclosed
EP-0409002-A2 Process for nucleophilic derivatization of materials having an imide group conjugated to an aromatic moiety International Business Machines Corporation (US) 1991-01-23 EP disclosed
EP-0409003-A2 Derivatives of compounds containing a carbonyl group conjugated to an aromatic moiety and electrophilic methods of fabrication thereof International Business Machines Corporation (US) 1991-01-23 EP disclosed
EP-0374487-A2 Method for conditioning an organic polymeric material International Business Machines Corporation (US) 1990-06-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160333022-A1 WATER SOLUBLE 4-AZAPODOPHYLLOTOXIN ANALOGS AQP1, MTX1, AQP3 ATM 4097/4885MEN1 804/4885KMT2A 1742/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.