Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 4/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | G6PD | P11413 | 1/20 | 0.33 |
| ▸ | TYMP | P19971 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4501948 | 0.77 | PKM (1.00) | PKMMAPTKDM4ETDP1POLB | |
| SCHEMBL191740 | 0.71 | G6PD (0.53) | MAPTKDM4EMEN1CASP6KMT2A | |
| SCHEMBL4561128 | 0.71 | G6PD (0.53) | MAPTKDM4EMEN1CASP6KMT2A | |
| SCHEMBL5826221 | 0.64 | TYMP (0.45) | PKMMAPTKDM4ETDP1POLB | |
| SCHEMBL5234292 | 0.64 | HTT (0.49) | PKMMAPTKDM4ETDP1CASP6 | |
| Hydrochloric Acid SCHEMBL11320851 | 0.63 | HTT (0.47) | PKMMAPTKDM4ETDP1CASP6 | |
| SCHEMBL2386652 | 0.61 | PKM (0.66) | PKMMAPTKDM4ETDP1POLB | |
| SCHEMBL9357304 | 0.60 | PKM (0.44) | PKMMAPTKDM4ETDP1MEN1 | |
| SCHEMBL1730 | 0.59 | PKM (0.61) | PKMMAPTKDM4ETDP1MEN1 | |
| SCHEMBL2386649 | 0.59 | PKM (0.61) | PKMMAPTKDM4ETDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004076425-A1 | IMPROVED SYNTHESIS OF MACROCYCLIC TETRAAMIDO COMPOUNDS AND NEW METAL INSERTION PROCESS | CARNEGIE MELLON UNIVERSITY (US) | 2004-09-10 | — | — | WO | disclosed |