Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 8/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6497809 | 0.91 | MCL1 (0.41) | MCL1MAPTAGBL2FFAR4ALDH1A1 | |
| SCHEMBL6920280 | 0.86 | PDE3B (0.42) | MCL1MAPTFFAR4ALDH1A1GAA | |
| SCHEMBL6492273 | 0.83 | MCL1 (0.39) | MCL1MAPTAGBL2FFAR4ALDH1A1 | |
| SCHEMBL6489825 | 0.82 | L3MBTL1 (0.43) | MCL1MAPTALDH1A1GAAL3MBTL1 | |
| SCHEMBL6922932 | 0.80 | MAPK1 (0.41) | MCL1AGBL2FFAR4ALDH1A1GAA | |
| SCHEMBL6491201 | 0.79 | MCL1 (0.43) | MCL1MAPTFFAR4ALDH1A1BCL2L1 | |
| SCHEMBL6500708 | 0.78 | MCL1 (0.47) | MCL1BCL2L1 | |
| SCHEMBL6490952 | 0.78 | ALOX5AP (0.43) | MCL1FFAR4ALDH1A1GAAMEN1 | |
| SCHEMBL6489538 | 0.77 | MCL1 (0.42) | MCL1MAPTFFAR4ALDH1A1BCL2L1 | |
| SCHEMBL6490678 | 0.77 | MCL1 (0.41) | MCL1FFAR4BCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004108686-A2 | BENZIMIDAZOLE COMPOUNDS HAVING HYPOGLYCEMIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-12-16 | — | — | WO | disclosed |