Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 12/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7196031 | 0.83 | MRGPRX4 (0.42) | ALOX5APMRGPRX4MEN1KMT2A | |
| SCHEMBL7196034 | 0.82 | MRGPRX4 (0.41) | PPARGMRGPRX4MEN1KMT2ANR1H4 | |
| SCHEMBL6920280 | 0.82 | PDE3B (0.42) | ALOX5APMEN1KMT2A | |
| SCHEMBL7192439 | 0.81 | MRGPRX4 (0.40) | MRGPRX4MEN1KMT2A | |
| SCHEMBL6488591 | 0.81 | ALOX5AP (0.44) | PPARGALOX5AP | |
| SCHEMBL7169905 | 0.77 | MCL1 (0.35) | PPARGNR1H4 | |
| SCHEMBL7191530 | 0.76 | AGTR1 (0.40) | MRGPRX4MEN1KMT2A | |
| SCHEMBL7196721 | 0.76 | PPARG (0.46) | PPARGALOX5APMRGPRX4 | |
| SCHEMBL6490693 | 0.75 | MRGPRX4 (0.43) | ALOX5APMRGPRX4 | |
| SCHEMBL6490952 | 0.73 | ALOX5AP (0.43) | ALOX5APMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004108686-A2 | BENZIMIDAZOLE COMPOUNDS HAVING HYPOGLYCEMIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-12-16 | — | — | WO | disclosed |