Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | ALB | P02768 | 5/20 | 0.50 |
| ▸ | CCR8 | P51685 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.46 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | P4HB | P07237 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6349631 | 0.86 | ALB (0.52) | KMT2AMEN1ALBTP53SERPINE1 | |
| SCHEMBL13870885 | 0.84 | KMT2A (0.70) | LMNAKMT2AALDH1A1MEN1ALB | |
| SCHEMBL17115694 | 0.84 | LMNA (0.58) | LMNAKMT2AALDH1A1TP53HPGD | |
| SCHEMBL6352325 | 0.83 | KMT2A (0.49) | LMNAKMT2AALDH1A1MEN1ALB | |
| SCHEMBL17115714 | 0.83 | ALDH1A1 (0.60) | LMNAKMT2AALDH1A1P4HBMAPT | |
| SCHEMBL6348185 | 0.81 | MCOLN3 (0.60) | LMNAKMT2AALDH1A1MEN1ALB | |
| SCHEMBL6819989 | 0.81 | ALB (0.54) | LMNAKMT2AALDH1A1MEN1ALB | |
| SCHEMBL6356973 | 0.81 | KMT2A (0.51) | KMT2AALDH1A1MEN1ALBSERPINE1 | |
| SCHEMBL6354039 | 0.80 | TP53 (0.69) | ALDH1A1ALBTP53MAPT | |
| SCHEMBL6359330 | 0.80 | TP53 (0.72) | KMT2AALDH1A1MEN1ALBTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004018414-A2 | ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | claimed |