Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | SIRT2 | Q8IXJ6 | 6/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | ALB | P02768 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6355513 | 0.90 | ALB (0.56) | MCOLN3L3MBTL1MEN1KMT2AGAA | |
| SCHEMBL6352311 | 0.84 | APEX1 (0.44) | MCOLN3L3MBTL1SIRT2MEN1KMT2A | |
| SCHEMBL6349631 | 0.83 | ALB (0.52) | SIRT2MEN1KMT2AAPEX1ALB | |
| SCHEMBL6920399 | 0.81 | LMNA (0.52) | MEN1KMT2AALBLMNATP53 | |
| SCHEMBL6350777 | 0.80 | SIRT2 (0.56) | SIRT2MEN1KMT2AGAAAPEX1 | |
| SCHEMBL6352847 | 0.80 | SIRT2 (0.52) | SIRT2MEN1KMT2AAPEX1ALB | |
| SCHEMBL6352026 | 0.79 | SIRT2 (0.51) | SIRT2MEN1KMT2AGAAAPEX1 | |
| SCHEMBL6349541 | 0.79 | SIRT2 (0.51) | SIRT2MEN1KMT2AGAAAPEX1 | |
| SCHEMBL6353090 | 0.79 | SIRT2 (0.56) | SIRT2MEN1KMT2AGAAAPEX1 | |
| SCHEMBL6833721 | 0.79 | MCOLN3 (0.44) | MCOLN3L3MBTL1MEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | PHARMACIA & UPJOHN COMPANY | 2005-05-26 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | CLPP, SPOUT1, SAMHD1 | MCOLN3 3980/4885L3MBTL1 3559/4885SIRT2 3380/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.