Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 19/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.56 |
| ▸ | HTR2A | P28223 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6829836 | 0.80 | HTR6 (0.60) | HTR6CYP3A4CYP2D6HTR2A | |
| SCHEMBL6826369 | 0.79 | HTR6 (0.55) | HTR6CYP3A4CYP2D6HTR2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL6826441 | 0.79 | HTR6 (0.59) | HTR6CYP3A4CYP2D6HTR2A | |
| SCHEMBL947264 | 0.77 | HTR6 (1.00) | HTR6CYP3A4CYP2D6HTR2AADRA2A | |
| SCHEMBL6830686 | 0.73 | HTR6 (0.66) | HTR6CYP3A4CYP2D6HTR2AALDH1A1 | |
| SCHEMBL6928279 | 0.73 | HTR6 (0.53) | HTR6CYP3A4CYP2D6POLB | |
| SCHEMBL947806 | 0.72 | HTR6 (1.00) | HTR6CYP3A4CYP2D6HTR2AADRA2A | |
| SCHEMBL29646236 | 0.72 | HTR6 (1.00) | HTR6CYP3A4CYP2D6HTR2A | |
| SCHEMBL947846 | 0.72 | HTR6 (1.00) | HTR6CYP3A4CYP2D6HTR2A | |
| SCHEMBL949684 | 0.71 | HTR6 (1.00) | HTR6CYP3A4CYP2D6HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004108671-A1 | SUBSTITUTED INDOLES WITH SEROTONIN RECEPTOR AFFINITY, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-12-16 | — | — | WO | disclosed |