Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 18/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6831378 | 0.83 | HTR6 (0.56) | HTR6CYP3A4CYP2D6 | |
| SCHEMBL6920527 | 0.73 | HTR6 (0.68) | HTR6CYP3A4CYP2D6POLB | |
| SCHEMBL6829140 | 0.71 | HRH3 (0.55) | CYP3A4CYP2D6KDM4ETSHRPOLB | |
| SCHEMBL949684 | 0.69 | HTR6 (1.00) | HTR6CYP3A4CYP2D6 | |
| SCHEMBL29646284 | 0.69 | HTR6 (1.00) | HTR6CYP3A4CYP2D6 | |
| SCHEMBL6826181 | 0.69 | HTR6 (0.48) | HTR6CYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL19629781 | 0.69 | HTR6 (0.98) | HTR6CYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL29646259 | 0.69 | HTR6 (0.98) | HTR6CYP3A4CYP2D6 | |
| SCHEMBL947210 | 0.68 | HTR6 (0.74) | HTR6CYP3A4CYP2D6 | |
| SCHEMBL946222 | 0.67 | HTR6 (1.00) | HTR6CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004108671-A1 | SUBSTITUTED INDOLES WITH SEROTONIN RECEPTOR AFFINITY, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-12-16 | — | — | WO | disclosed |