Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11119765 | 0.81 | ALDH1A1 (0.39) | ALDH1A1MAPTTDP1HSD17B10CTSD | |
| SCHEMBL28331233 | 0.78 | ALDH1A1 (0.37) | ALDH1A1MAPTTDP1L3MBTL1MAPK1 | |
| SCHEMBL11300447 | 0.78 | ALDH1A1 (0.41) | ALDH1A1MAPTTDP1HSD17B10CTSD | |
| SCHEMBL25333055 | 0.75 | ALDH1A1 (0.42) | ALDH1A1MAPTTDP1HSD17B10CTSD | |
| SCHEMBL3937557 | 0.75 | ALDH1A1 (0.39) | ALDH1A1MAPTTDP1HSD17B10CTSD | |
| SCHEMBL11313866 | 0.75 | IDO1 (0.42) | ALDH1A1MAPTTDP1HSD17B10CTSD | |
| SCHEMBL28415827 | 0.75 | TDP1 (0.42) | ALDH1A1MAPTTDP1HSD17B10CTSD | |
| SCHEMBL45188 | 0.75 | KCNH3 (0.49) | ALDH1A1MAPTTDP1HSD17B10CTSD | |
| SCHEMBL2940229 | 0.75 | MEN1 (0.42) | ALDH1A1MAPTTDP1HSD17B10CTSD | |
| SCHEMBL3366323 | 0.73 | HDAC1 (0.42) | ALDH1A1MAPTTDP1HSD17B10CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0315862-B1 | Aromatically fluorinated fluoromethoxy- and fluoromethylthio-amino benzenes and their preparation | BAYER AG (DE) | 1994-04-13 | — | — | EP | claimed |
| WO-2023143356-A1 | METHIONINE ADENOSYLTRANSFERASE 2A INHIBITOR FOR TREATING MTAP DELETION-TYPE CANCER | 勤浩医药（苏州）有限公司 | 2023-08-03 | — | — | WO | disclosed |
| US-20210289794-A1 | COMPOSITIONS AND RELATED METHODS FOR AGRICULTURE | FLAGSHIP PIONEERING INNOVATIONS V, INC. | 2021-09-23 | — | — | US | disclosed |
| WO-2004072046-A2 | QUINOLINE DERIVATIVES AND THEIR USE FOR MODULATION OF LXR ACTIVITY | CAREX S.A. (FR) | 2004-08-26 | — | — | WO | disclosed |
| EP-0794936-B1 | METHOD FOR PREPARING FLUOROANILINES FROM NITROFLUOROBENZENE COMPOUNDS | RHODIA CHIMIE SA (FR) | 1999-03-17 | — | — | EP | disclosed |
| US-5856577-A | Process for the preparation of fluoroanilines from fluorinated nitrated benzene compounds | RHONE-POULENC CHIMIE (FR) | 1999-01-05 | — | — | US | disclosed |
| EP-0875497-A2 | Method for preparing fluoroanilines from nitrofluorobenzene compounds | RHODIA CHIMIE (FR) | 1998-11-04 | — | — | EP | disclosed |
| EP-0794936-A1 | METHOD FOR PREPARING FLUOROANILINES FROM NITROFLUOROBENZENE COMPOUNDS | RHONE-POULENC CHIMIE (FR) | 1997-09-17 | — | — | EP | disclosed |
| WO-1996016926-A1 | METHOD FOR PREPARING FLUOROANILINES FROM NITROFLUOROBENZENE COMPOUNDS | RHONE-POULENC CHIMIE (FR) | 1996-06-06 | — | — | WO | disclosed |
| EP-0315862-B1 | Aromatically fluorinated fluoromethoxy- and fluoromethylthio-amino benzenes and their preparation | BAYER AG (DE) | 1994-04-13 | — | — | EP | disclosed |
| EP-0315862-A2 | Aromatically fluorinated fluoromethoxy- and fluoromethylthio-amino benzenes and their preparation | BAYER AG (DE) | 1989-05-17 | — | — | EP | disclosed |
| EP-0315862-A2 | Aromatically fluorinated fluoromethoxy- and fluoromethylthio-amino benzenes and their preparation | BAYER AG (DE) | 1989-05-17 | — | — | EP | disclosed |
| EP-0000156-A1 | 2-Arylamino-3,5-dinitro-benzotrifluorides, process for their preparation and their use as pesticides. | BAYER AG (DE) | 1979-01-10 | — | — | EP | disclosed |