Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10358898 | 0.81 | ALDH1A1 (0.36) | ALDH1A1TDP1HSD17B10CTSDTSHR | |
| SCHEMBL11313866 | 0.75 | IDO1 (0.42) | ALDH1A1TDP1HSD17B10CTSDTSHR | |
| SCHEMBL28415827 | 0.75 | TDP1 (0.42) | ALDH1A1TDP1HSD17B10CTSDTSHR | |
| SCHEMBL6920608 | 0.75 | ALDH1A1 (0.42) | ALDH1A1TDP1HSD17B10CTSDTSHR | |
| SCHEMBL45188 | 0.75 | KCNH3 (0.49) | ALDH1A1TDP1HSD17B10CTSDTSHR | |
| SCHEMBL25333055 | 0.75 | ALDH1A1 (0.42) | ALDH1A1TDP1HSD17B10CTSDTSHR | |
| Ethane SCHEMBL11766692 | 0.73 | KCNH3 (0.47) | ALDH1A1TDP1HSD17B10CTSDTSHR | |
| SCHEMBL311949 | 0.73 | TSHR (0.50) | ALDH1A1TSHRPTGS2L3MBTL1PTGS1 | |
| SCHEMBL2911694 | 0.73 | HDAC1 (0.42) | ALDH1A1TDP1HSD17B10CTSDTSHR | |
| SCHEMBL3366323 | 0.73 | HDAC1 (0.42) | ALDH1A1TDP1HSD17B10CTSDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3989756-A | RANEY CATALYST, DEHALOGENATION INHIBITOR | NIPPON KAYAKU KABUSHIKI KAISHA (JA) | 1976-11-02 | — | — | US | claimed |
| EP-2043644-A1 | NF- B INHIBITOR | Otsuka Pharmaceutical Co., Ltd. (JP) | 2009-04-08 | — | — | EP | disclosed |
| WO-2008010601-A1 | NF- ϰB INHIBITOR | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2008-01-24 | — | — | WO | disclosed |
| US-20070240618-A1 | High-Purity Naphthol as Pigments | ROHR ULRIKE | 2007-10-18 | — | — | US | disclosed |
| US-20070213516-A1 | Process For Producing High-Purity Azo Dyes | HOELLEIN VOLKER | 2007-09-13 | — | — | US | disclosed |
| EP-1740658-A1 | HIGH-PURITY NAPHTHOL AS PIGMENTS | Clariant Produkte (Deutschland) GmbH (DE) | 2007-01-10 | — | — | EP | disclosed |
| EP-1740659-A1 | PROCESS FOR PRODUCING HIGH-PURITY AZO DYES | Clariant Produkte (Deutschland) GmbH (DE) | 2007-01-10 | — | — | EP | disclosed |
| WO-2005105927-A1 | PROCESS FOR PRODUCING HIGH-PURITY AZO DYES | CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) | 2005-11-10 | — | — | WO | disclosed |
| WO-2005105928-A1 | HIGH-PURITY NAPHTHOL AS PIGMENTS | CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) | 2005-11-10 | — | — | WO | disclosed |
| US-3947247-A | STABILIZER COMPOSITION FOR DYESTUFFS | CENTRAL MICHIGAN UNIVERSITY BOARD OF TRUSTEES (US) | 1976-03-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070240618-A1 | High-Purity Naphthol as Pigments | SNX2, NPM1, XPA | ALDH1A1 1715/4885TDP1 3038/4885HSD17B10 2532/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.