Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MAOB | P27338 | 7/20 | 0.51 |
| ▸ | MMP12 | P39900 | 2/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 5/20 | 0.46 |
| ▸ | PPARA | Q07869 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27790636 | 0.86 | IDO1 (0.47) | IDO1KMT2AMAOBMMP12MMP1 | |
| SCHEMBL6026962 | 0.86 | IDO1 (0.53) | IDO1KMT2AMAOBMMP12MMP1 | |
| Hydrochloric Acid SCHEMBL4484631 | 0.85 | IDO1 (0.49) | IDO1KMT2AMAOBMMP12MMP1 | |
| SCHEMBL11740623 | 0.83 | MAOB (0.52) | IDO1KMT2AMAOBMMP12MMP1 | |
| SCHEMBL20015915 | 0.83 | SMN1; SMN2 (0.51) | KMT2AMEN1 | |
| SCHEMBL10175183 | 0.83 | MAOB (0.51) | IDO1KMT2AMAOBMMP12MMP1 | |
| SCHEMBL3335304 | 0.82 | IDO1 (0.58) | IDO1KMT2AMAOBMMP12MMP1 | |
| SCHEMBL25290310 | 0.82 | IDO1 (0.57) | IDO1KMT2AMAOBMMP12MMP1 | |
| SCHEMBL6026958 | 0.81 | MMP12 (0.49) | IDO1KMT2AMAOBMMP12MMP1 | |
| SCHEMBL23049787 | 0.81 | PRKCA (0.60) | IDO1MAOBMMP12MMP1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111057024-A | Sydneone and sydneone imine compound and preparation method and application thereof | 华东理工大学 | 2020-04-24 | — | — | CN | disclosed |
| CN-100410236-C | Substituted methylene amide derivatives as protein tyrosine phosphatase modulators | APPLIED RESEARCH SYSTEMS (CH) | 2008-08-13 | — | — | CN | disclosed |
| CN-1633410-A | Substituted methylene amide derivatives as protein tyrosine phosphatase modulators | APPLIED RESEARCH SYSTEMS (AN) | 2005-06-29 | — | — | CN | disclosed |
| EP-1470102-A1 | SUBSTITUTED METHYLENE AMIDE DERIVATIVES AS MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPS) | Applied Research Systems ARS Holding N.V. (AN) | 2004-10-27 | — | — | EP | disclosed |
| WO-2003064376-A1 | SUBSTITUTED METHYLENE AMIDE DERIVATIVES AS MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPS) | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2003-08-07 | — | — | WO | disclosed |