Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.65 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | SRC | P12931 | 1/20 | 0.56 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | PGR | P06401 | 1/20 | 0.48 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.46 |
| ▸ | PRKDC | P78527 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7723992 | 0.86 | SRC (0.53) | CYP19A1P2RX4MEN1KMT2AALDH1A1 | |
| SCHEMBL28735017 | 0.86 | CYP19A1 (0.56) | CYP19A1P2RX4MEN1KMT2AALDH1A1 | |
| SCHEMBL29588112 | 0.86 | CYP19A1 (0.56) | CYP19A1P2RX4MEN1KMT2AALDH1A1 | |
| SCHEMBL6924327 | 0.85 | SRC (0.51) | CYP19A1P2RX4MEN1KMT2AALDH1A1 | |
| SCHEMBL6923669 | 0.84 | SRC (0.50) | CYP19A1P2RX4MEN1KMT2AALDH1A1 | |
| SCHEMBL6923659 | 0.84 | KMT2A (0.51) | CYP19A1P2RX4MEN1KMT2AALDH1A1 | |
| SCHEMBL6926546 | 0.83 | CYP19A1 (0.47) | CYP19A1P2RX4MEN1KMT2AALDH1A1 | |
| SCHEMBL6927392 | 0.82 | ATM (0.53) | CYP19A1P2RX4MEN1KMT2AALDH1A1 | |
| SCHEMBL6924122 | 0.82 | PLA2G2A (0.46) | CYP19A1P2RX4MEN1KMT2AALDH1A1 | |
| SCHEMBL6920467 | 0.81 | PLA2G2A (0.55) | P2RX4KMT2APLA2G2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1169789-C | Aminoalkoxy carbazoles for the treatment of CNS diseases | 法玛西雅厄普约翰美国公司 | 2004-10-06 | — | — | CN | disclosed |
| US-6514968-B1 | Treating a disease or condition in a mammal wherein the 5-HT receptor is implicated and modulation of 5-HT function is desired comprising | PHARMACIA & UPJOHN COMPANY | 2003-02-04 | — | — | US | disclosed |
| CN-1372547-A | Aminoalkoxy carbazoles for the treatment of CNS diseases | UPJOHN CO (US) | 2002-10-02 | — | — | CN | disclosed |
| EP-1210329-A2 | AMINOALKOXY CARBAZOLES AND THEIR USE AS 5-HT LIGANDS | PHARMACIA & UPJOHN COMPANY (US) | 2002-06-05 | — | — | EP | disclosed |
| WO-2001017963-A2 | AMINOALKOXY CARBAZOLES AND THEIR USE AS 5-HT LIGANDS | PHARMACIA & UPJOHN COMPANY (US) | 2001-03-15 | — | — | WO | disclosed |