Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 2/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | PLA2G2A | P14555 | 7/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | PRKDC | P78527 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6924327 | 0.87 | SRC (0.51) | SRCCYP19A1MEN1KMT2AMAPT | |
| SCHEMBL6921173 | 0.86 | CYP19A1 (0.65) | SRCCYP19A1MEN1KMT2AMAPT | |
| SCHEMBL6923659 | 0.86 | KMT2A (0.51) | SRCCYP19A1MEN1KMT2AMAPT | |
| SCHEMBL6923669 | 0.86 | SRC (0.50) | SRCCYP19A1MEN1KMT2AMAPT | |
| SCHEMBL6920467 | 0.83 | PLA2G2A (0.55) | KMT2APLA2G2AP2RX4MAPK1 | |
| SCHEMBL6984365 | 0.82 | PLA2G2A (0.55) | SRCCYP19A1MEN1KMT2AMAPT | |
| Pyridine SCHEMBL7506032 | 0.80 | SRC (0.44) | SRCCYP19A1MEN1KMT2AMAPT | |
| SCHEMBL6921048 | 0.79 | HDAC1 (0.43) | SRCMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL6924122 | 0.76 | PLA2G2A (0.46) | SRCCYP19A1MEN1KMT2AMAPT | |
| SCHEMBL6926577 | 0.76 | MAPT (0.43) | MEN1KMT2AMAPTALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6407261-B1 | OXIDIZING THE CORRESPONDING KETONE COMPOUND BY HEATING WITH A SUKFINATING COMPOUND | ELI LILLY AND COMPANY | 2002-06-18 | — | — | US | disclosed |
| EP-1071661-A4 | PROCESS FOR PREPARING 4-HYDROXY INDOLE, INDAZOLE AND CARBAZOLE COMPOUNDS | LILLY CO ELI (US) | 2001-08-22 | — | — | EP | disclosed |
| EP-1071661-A1 | PROCESS FOR PREPARING 4-HYDROXY INDOLE, INDAZOLE AND CARBAZOLE COMPOUNDS | ELI LILLY AND COMPANY (US) | 2001-01-31 | — | — | EP | disclosed |
| WO-1999054295-A1 | PROCESS FOR PREPARING 4-HYDROXY INDOLE, INDAZOLE AND CARBAZOLE COMPOUNDS | ELI LILLY AND COMPANY (US) | 1999-10-28 | — | — | WO | disclosed |