Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | SRC | P12931 | 3/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | RGS12 | O14924 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyridine SCHEMBL7510140 | 0.91 | PLA2G2A (0.41) | CYP19A1PLA2G2AMEN1KMT2AALDH1A1 | |
| SCHEMBL6924605 | 0.88 | MEN1 (0.43) | PLA2G2AMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL6924122 | 0.84 | PLA2G2A (0.46) | CYP19A1PLA2G2AMEN1KMT2AALDH1A1 | |
| SCHEMBL6927392 | 0.84 | ATM (0.53) | CYP19A1PLA2G2AMEN1KMT2AALDH1A1 | |
| SCHEMBL6921173 | 0.83 | CYP19A1 (0.65) | CYP19A1PLA2G2AMEN1KMT2AALDH1A1 | |
| SCHEMBL6924327 | 0.76 | SRC (0.51) | CYP19A1PLA2G2AMEN1KMT2AALDH1A1 | |
| SCHEMBL6921052 | 0.75 | MEN1 (0.43) | PLA2G2AMEN1KMT2AALDH1A1MAPT | |
| Bromide SCHEMBL7510146 | 0.75 | ESR1 (0.38) | CYP19A1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL7723992 | 0.74 | SRC (0.53) | CYP19A1PLA2G2AMEN1KMT2AALDH1A1 | |
| SCHEMBL6926616 | 0.73 | LMNA (0.44) | PLA2G2AMEN1KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1169789-C | Aminoalkoxy carbazoles for the treatment of CNS diseases | 法玛西雅厄普约翰美国公司 | 2004-10-06 | — | — | CN | disclosed |
| US-6514968-B1 | Treating a disease or condition in a mammal wherein the 5-HT receptor is implicated and modulation of 5-HT function is desired comprising | PHARMACIA & UPJOHN COMPANY | 2003-02-04 | — | — | US | disclosed |
| CN-1372547-A | Aminoalkoxy carbazoles for the treatment of CNS diseases | UPJOHN CO (US) | 2002-10-02 | — | — | CN | disclosed |
| EP-1210329-A2 | AMINOALKOXY CARBAZOLES AND THEIR USE AS 5-HT LIGANDS | PHARMACIA & UPJOHN COMPANY (US) | 2002-06-05 | — | — | EP | disclosed |
| WO-2001017963-A2 | AMINOALKOXY CARBAZOLES AND THEIR USE AS 5-HT LIGANDS | PHARMACIA & UPJOHN COMPANY (US) | 2001-03-15 | — | — | WO | disclosed |