Sugi Predict

Sugi Predict / Compounds / SCHEMBL692131

SCHEMBL692131

SCHEMBL692131

Cc1ccc(S(=O)(=O)Cl)c(C)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 4/20 0.47
▸ MAPT P10636 3/20 0.47
▸ HPGD P15428 2/20 0.47
▸ POLB P06746 1/20 0.47
▸ ALOX12 P18054 1/20 0.47
▸ GFER P55789 1/20 0.47
▸ KMT2A Q03164 1/20 0.46
▸ SMN1; SMN2 Q16637 3/20 0.45
▸ LMNA P02545 3/20 0.45
▸ GAA P10253 1/20 0.45
▸ MEP1B Q16820 1/20 0.45
▸ RAPGEF4 Q8WZA2 3/20 0.44
▸ KDM4E B2RXH2 1/20 0.44
▸ F2 P00734 1/20 0.44
▸ PKM P14618 1/20 0.42
▸ MAPK1 P28482 1/20 0.42
▸ HTT P42858 1/20 0.42
▸ MCL1 Q07820 1/20 0.42
▸ HSD17B10 Q99714 1/20 0.41
▸ TRPV4 Q9HBA0 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29627448 0.84 TRPV4 (0.42) ALDH1A1MAPTHPGDPOLBALOX12
SCHEMBL2426442 0.84 TRPV4 (0.42) ALDH1A1MAPTHPGDPOLBALOX12
SCHEMBL11496917 0.84 HPGD (0.38) ALDH1A1MAPTHPGDPOLBALOX12
SCHEMBL742725 0.82 KMT2A (0.49) ALDH1A1MAPTHPGDPOLBKMT2A
SCHEMBL29642997 0.82 KMT2A (0.49) ALDH1A1MAPTHPGDPOLBKMT2A
SCHEMBL11348441 0.82 TRPV4 (0.41) ALDH1A1HPGDGAATRPV4L3MBTL1
SCHEMBL2236507 0.81 ALDH1A1 (0.50) ALDH1A1MAPTHPGDPOLBALOX12
SCHEMBL7896750 0.81 ALDH1A1 (0.50) ALDH1A1MAPTHPGDPOLBALOX12
SCHEMBL11792843 0.80 TDP1 (0.42) ALDH1A1LMNAGAARAPGEF4PKM
SCHEMBL29907222 0.80 TRPV4 (0.53) ALDH1A1KMT2ASMN1; SMN2LMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 272 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119490439-A Preparation method of arylsulfonyl amino quaternary ammonium salt antibacterial agent 苏州华道生物药业股份有限公司 2025-02-21 — — CN claimed
CN-111615522-B Process for the synthesis of cyclodextrin derivatives 摩迪康公司 2023-04-18 — — CN claimed
US-20200377621-A1 PROCESS FOR THE SYNTHESIS OF A CYCLODEXTRIN DERIVATIVE MEDICHEM, S.A. (ES) 2020-12-03 — — US claimed
EP-3717521-A1 PROCESS FOR THE SYNTHESIS OF A CYCLODEXTRIN DERIVATIVE Medichem, S.A. (ES) 2020-10-07 — — EP claimed
CN-111615522-A Process for the synthesis of cyclodextrin derivatives 摩迪康公司 2020-09-01 — — CN claimed
WO-2019102009-A1 PROCESS FOR THE SYNTHESIS OF A CYCLODEXTRIN DERIVATIVE MEDICHEM, S.A. (ES) 2019-05-31 — — WO claimed
CN-109516987-A A kind of AVM hereinafter Batan centre preparation 江西富祥药业股份有限公司 2019-03-26 — — CN claimed
CN-109503693-A A kind of new process efficiently synthesizing Aramchol for raw material using cholic acid and arachidic acid 合肥工业大学 2019-03-22 — — CN claimed
CN-122080012-A Thienopyrimidine derivative, preparation method, application and pharmaceutical composition thereof — 2026-05-26 — — CN disclosed
CN-117177975-B Pyrimido [5,4, D ] pyrimidine compounds, compositions comprising the same and uses thereof 蒙特利尔大学 2026-05-19 — — CN disclosed
CN-117659017-B TRPML1/2 modulator compound, pharmaceutical composition, preparation method and application thereof 北京华益健康药物研究中心 2026-05-15 — — CN disclosed
US-20260014119-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF BIOGEN MA INC (US) 2026-01-15 — — US disclosed
US-12479842-B2 Pyrido[3,2-d]pyrimidine compounds uses thereof for treating a proliferative disease UNIVERSITE DE MONTREAL (CA) 2025-11-25 — — US disclosed
US-20250270207-A1 PYRIDO[3,2-D]PYRIMIDINE COMPOUNDS USES THEREOF FOR TREATING A PROLIFERATIVE DISEASE UNIVERSITE DE MONTREAL (CA) 2025-08-28 — — US disclosed
US-3988228-A Photopolymerizable polymeric compositions containing halogen containing aromatic ketones EASTMAN KODAK COMPANY (US) 1976-10-26 — — US disclosed
US-3966573-A HALOGENATED HYDROCARBONS, CARBONYL COMPOUNDS, ORGANO-NITROGEN, PHOSPHOROUS, ARSENIC, BISMUTH, OR ANTIMONY COMPOUNDS SUN CHEMICAL CORPORATION (US) 1976-06-29 — — US disclosed
US-3962056-A MOLDING, COATING EASTMAN KODAK COMPANY (US) 1976-06-08 — — US disclosed
US-3962055-A MOLDING, COATING EASTMAN KODAK COMPANY (US) 1976-06-08 — — US disclosed
US-3945992-A DISAZO DYES FOR POLYAMIDES BAYER AKTIENGESELLSCHAFT (DT) 1976-03-23 — — US disclosed
US-3933682-A Photopolymerization co-initiator systems SUN CHEMICAL CORPORATION (US) 1976-01-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014119-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF EBP, EBPL, ELP1 ALDH1A1 3608/4885MAPT 4670/4885HPGD 2593/4885
US-20250270207-A1 PYRIDO[3,2-D]PYRIMIDINE COMPOUNDS USES THEREOF FOR TREATING A PROLIFERATIVE DISEASE BRAF, NRAS, KRAS ALDH1A1 1636/4885MAPT 2948/4885HPGD 358/4885
US-12479842-B2 Pyrido[3,2-d]pyrimidine compounds uses thereof for treating a proliferative disease BRAF, NRAS, DPYD ALDH1A1 1619/4885MAPT 3015/4885HPGD 354/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.