Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | PDIA6 | Q15084 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 3/20 | 0.34 |
| ▸ | CA2 | P00918 | 3/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11496917 | 0.92 | HPGD (0.38) | TRPV4L3MBTL1ALDH1A1CYP3A4TSHR | |
| SCHEMBL11494371 | 0.90 | HTR6 (0.45) | L3MBTL1ALDH1A1TDP1HPGDCA1 | |
| SCHEMBL6111498 | 0.84 | TRPV4 (0.49) | TRPV4ALDH1A1CA1CA2CA12 | |
| SCHEMBL692131 | 0.82 | ALDH1A1 (0.47) | TRPV4L3MBTL1ALDH1A1HPGDGAA | |
| SCHEMBL30858654 | 0.80 | ACVR1 (0.45) | — | |
| SCHEMBL1199760 | 0.80 | TRPV4 (0.58) | TRPV4L3MBTL1ALDH1A1CYP3A4TP53 | |
| SCHEMBL6209563 | 0.80 | TRPV4 (0.40) | TRPV4L3MBTL1ALDH1A1TDP1HPGD | |
| SCHEMBL29948957 | 0.80 | TRPV4 (0.58) | TRPV4L3MBTL1ALDH1A1CYP3A4TP53 | |
| SCHEMBL11792843 | 0.80 | TDP1 (0.42) | TRPV4L3MBTL1ALDH1A1TDP1PDIA6 | |
| SCHEMBL181280 | 0.78 | TSHR (0.47) | TRPV4L3MBTL1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4278577-A | HEAT RESISTANCE | AMERICAN CYANAMID COMPANY (US) | 1981-07-14 | — | — | US | disclosed |
| EP-0029090-A2 | Sulfon amides containing a hindered phenol; stabilized composition containing a synthetic polymer and said sulfon amides | AMERICAN CYANAMID COMPANY (US) | 1981-05-27 | — | — | EP | disclosed |