Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.63 |
| ▸ | RAB9A | P51151 | 2/20 | 0.63 |
| ▸ | GPR142 | Q7Z601 | 6/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.53 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.53 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.53 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.52 |
| ▸ | CES2 | O00748 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.51 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9001768 | 0.87 | POLB (0.62) | POLBRAB9AALDH1A1HPGDKDM4E | |
| SCHEMBL23716727 | 0.85 | GPR142 (0.61) | POLBRAB9AGPR142KMT2ATAS1R3 | |
| SCHEMBL17008891 | 0.85 | GPR142 (0.61) | POLBRAB9AGPR142KMT2ATAS1R3 | |
| SCHEMBL20473390 | 0.85 | GPR142 (0.61) | POLBRAB9AGPR142KMT2ATAS1R3 | |
| SCHEMBL17008901 | 0.82 | GPR142 (0.61) | POLBRAB9AGPR142TAS1R3TAS1R1 | |
| SCHEMBL19797862 | 0.82 | GPR142 (0.61) | POLBRAB9AGPR142TAS1R3TAS1R1 | |
| SCHEMBL2227459 | 0.81 | POLB (0.66) | POLBRAB9AALDH1A1HPGDKDM4E | |
| SCHEMBL3457039 | 0.81 | ALDH1A1 (0.57) | POLBRAB9AALDH1A1HPGDKDM4E | |
| SCHEMBL23716711 | 0.81 | GPR142 (0.65) | POLBRAB9AGPR142TAS1R3TAS1R1 | |
| SCHEMBL23839836 | 0.80 | HSD11B1 (0.58) | POLBRAB9AGPR142ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004087669-A1 | NOVEL QUINOLINE, TETRAHYDROQUINAZOLINE, AND PYRIMIDINE DERIVATIVES AND METHODS OF TREATMENT RELATED TO THE USE THEREOF | TAISHO PHARMACEUTICAL CO. LTD. (JP) | 2004-10-14 | — | — | WO | claimed |