Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6922376 | 0.74 | SCN10A (0.30) | — | |
| SCHEMBL5791947 | 0.73 | ALDH1A1 (0.43) | MAPTALDH1A1LMNACYP1A2 | |
| SCHEMBL11191922 | 0.72 | HSP90AA1 (0.38) | MAPTALDH1A1LMNAGAA | |
| Hydrochloric Acid SCHEMBL8709929 | 0.71 | ALDH1A1 (0.33) | MAPTALDH1A1LMNAGAA | |
| SCHEMBL5674014 | 0.70 | — | — | |
| Hydrochloric Acid SCHEMBL11466216 | 0.69 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL3667065 | 0.69 | KDM4E (0.39) | ALDH1A1 | |
| SCHEMBL3028139 | 0.67 | — | — | |
| SCHEMBL4575373 | 0.61 | MAPT (0.37) | MAPTALDH1A1GAACYP1A2 | |
| SCHEMBL11280088 | 0.59 | KDM4E (0.58) | ALDH1A1LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004074258-A1 | NOVEL SULPHATED IMIDAZOLE DERIVATIVES, METHOD FOR PRODUCTION THEREOF, NOVEL INTERMEDIATES OBTAINED, APPLICATION THEREOF AS MEDICAMENTS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE ABOVE | CAILLE JEAN-CLAUDE (FR) | 2004-09-02 | — | — | WO | disclosed |
| EP-0465368-B1 | Sulfur derivatives of imidazole, process for their preparation, intermediates, their use as medicaments, and pharmaceutical compositions containing them | HOECHST MARION ROUSSEL INC (FR) | 1998-05-20 | — | — | EP | disclosed |
| US-5684028-A | ANGIOTENSIN II INHIBITORS | ROUSSEL UCLAF (FR) | 1997-11-04 | — | — | US | disclosed |
| US-5599830-A | ANGIOTENSIN INHIBITORS | ROUSSEL UCLAF (FR) | 1997-02-04 | — | — | US | disclosed |
| US-5412101-A | Angiotensin II inhibitor | ROUSSEL-UCLAF (FR) | 1995-05-02 | — | — | US | disclosed |
| EP-0465368-A1 | Sulfur derivatives of imidazole, process for their preparation, intermediates, their use as medicaments, and pharmaceutical compositions containing them | ROUSSEL UCLAF (FR) | 1992-01-08 | — | — | EP | disclosed |