SCHEMBL6922376

SCHEMBL6922376

CCSc1nc(C(C)CC)[nH]c1CO

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SCN10A Q9Y5Y9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6920932 0.77 ALDH1A1 (0.33) SCN10A
SCHEMBL6922119 0.74 MAPT (0.36)
SCHEMBL19087065 0.65
SCHEMBL23131296 0.60
SCHEMBL3690726 0.59 KDM4E (0.31)
SCHEMBL4351362 0.59 KDM4E (0.31)
SCHEMBL553364 0.59
SCHEMBL11481153 0.59 KDM4E (0.31)
SCHEMBL3031165 0.57 KDM4E (0.32)
SCHEMBL553008 0.57

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004074258-A1 NOVEL SULPHATED IMIDAZOLE DERIVATIVES, METHOD FOR PRODUCTION THEREOF, NOVEL INTERMEDIATES OBTAINED, APPLICATION THEREOF AS MEDICAMENTS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE ABOVE CAILLE JEAN-CLAUDE (FR) 2004-09-02 WO disclosed
EP-0465368-B1 Sulfur derivatives of imidazole, process for their preparation, intermediates, their use as medicaments, and pharmaceutical compositions containing them HOECHST MARION ROUSSEL INC (FR) 1998-05-20 EP disclosed
EP-0465368-A1 Sulfur derivatives of imidazole, process for their preparation, intermediates, their use as medicaments, and pharmaceutical compositions containing them ROUSSEL UCLAF (FR) 1992-01-08 EP disclosed