Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | G6PD | P11413 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2674642 | 0.81 | MEN1 (0.53) | MEN1KMT2AMAPTSMN1; SMN2MAPK1 | |
| SCHEMBL11197844 | 0.79 | MEN1 (0.50) | MEN1KMT2AMAPTSMN1; SMN2MAPK1 | |
| SCHEMBL11062887 | 0.79 | MEN1 (0.50) | MEN1KMT2AMAPTSMN1; SMN2MAPK1 | |
| SCHEMBL2910412 | 0.78 | MEN1 (0.49) | MEN1KMT2AMAPTSMN1; SMN2MAPK1 | |
| SCHEMBL7582686 | 0.75 | KMT2A (0.66) | MEN1KMT2AMAPTSMN1; SMN2MAPK1 | |
| SCHEMBL11066635 | 0.74 | MEN1 (0.45) | MEN1KMT2AMAPTSMN1; SMN2MAPK1 | |
| SCHEMBL27688081 | 0.74 | MMP2 (0.47) | MEN1KMT2AMAPTSMN1; SMN2MAPK1 | |
| SCHEMBL27688083 | 0.74 | MMP2 (0.47) | MEN1KMT2AMAPTSMN1; SMN2MAPK1 | |
| SCHEMBL2090421 | 0.73 | ATM (0.58) | MEN1KMT2AMAPTSMN1; SMN2ATM | |
| SCHEMBL9525229 | 0.73 | MAPT (0.54) | MEN1KMT2AMAPTSMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004065389-A1 | PYRROLOPYRIMIDINE DERIVATIVES USEFUL AS MODULATORS OF MULTIDRUG RESISTANCE | XENOVA LIMITED (GB) | 2004-08-05 | — | — | WO | disclosed |