Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 3/20 | 0.34 |
| ▸ | HTR3A | P46098 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.32 |
| ▸ | ICAM1 | P05362 | 3/20 | 0.32 |
| ▸ | SELE | P16581 | 3/20 | 0.32 |
| ▸ | VCAM1 | P19320 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6928487 | 0.78 | GAA (0.43) | ALDH1A1MAPTL3MBTL1TDP1HPGD | |
| SCHEMBL3547431 | 0.78 | HTR1A (0.45) | ALDH1A1MAPTL3MBTL1TDP1HPGD | |
| SCHEMBL3547996 | 0.73 | HTR1A (0.53) | ALDH1A1MAPTL3MBTL1TDP1HPGD | |
| SCHEMBL3544118 | 0.72 | HTR1A (0.44) | ALDH1A1MAPTL3MBTL1TDP1HPGD | |
| SCHEMBL5275317 | 0.71 | S1PR1 (0.41) | ALDH1A1HPGDLMNA | |
| SCHEMBL11393581 | 0.70 | POLB (0.31) | MAPTL3MBTL1 | |
| SCHEMBL2431139 | 0.70 | ACHE (0.44) | ALDH1A1MAPTTDP1GAAMEN1 | |
| SCHEMBL3537628 | 0.69 | HTR1A (0.50) | ALDH1A1MAPTL3MBTL1HPGDLMNA | |
| SCHEMBL6928587 | 0.69 | CYP2A6 (0.47) | ALDH1A1MAPTL3MBTL1TDP1HPGD | |
| SCHEMBL3544287 | 0.69 | MLYCD (0.46) | ALDH1A1MAPTL3MBTL1TDP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6518268-B1 | Telomerase inhibitors and methods of their use | GERON CORPORATION | 2003-02-11 | — | — | US | disclosed |
| WO-2001002377-A9 | TELOMERASE INHIBITORS AND METHODS OF THEIR USE | GERON CORP (US) | 2001-10-11 | — | — | WO | disclosed |
| EP-1109796-A1 | TELOMERASE INHIBITORS AND METHODS OF THEIR USE | Geron Corporation (US) | 2001-06-27 | — | — | EP | disclosed |
| WO-2001002377-A1 | TELOMERASE INHIBITORS AND METHODS OF THEIR USE | GERON CORPORATION (US) | 2001-01-11 | — | — | WO | disclosed |