Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6922339 | 1.00 | L3MBTL1 (0.38) | L3MBTL1MEN1KMT2AHSD17B10KDM4E | |
| SCHEMBL14598533 | 0.84 | L3MBTL1 (0.41) | L3MBTL1KMT2A | |
| SCHEMBL668722 | 0.79 | L3MBTL1 (0.34) | L3MBTL1 | |
| SCHEMBL14345693 | 0.74 | MEN1 (0.34) | MEN1KMT2AHSD17B10KDM4EALDH1A1 | |
| SCHEMBL10800721 | 0.72 | MEN1 (0.36) | MEN1KMT2A | |
| SCHEMBL221917 | 0.70 | GBA1 (0.41) | MEN1KMT2AHSD17B10KDM4EALDH1A1 | |
| SCHEMBL10800726 | 0.68 | MEN1 (0.34) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL12099149 | 0.67 | L3MBTL1 (0.34) | L3MBTL1KMT2A | |
| SCHEMBL1360935 | 0.65 | MMP1 (0.37) | — | |
| SCHEMBL27082407 | 0.65 | GAA (0.46) | MEN1KMT2AHSD17B10KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004024060-A2 | METALLOPROTEINASE INHIBITORS AND INTERMEDIATES FOR PREPARATION THEREOF | ASTRAZENECA AB (SE) | 2004-03-25 | — | — | WO | disclosed |