Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 2/20 | 0.32 |
| ▸ | PRKCA | P17252 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6922396 | 1.00 | MAPT (0.46) | MAPTMEN1KMT2AALDH1A1HCAR2 | |
| SCHEMBL6903532 | 0.97 | MAPT (0.48) | MAPTMEN1KMT2AALDH1A1HCAR2 | |
| SCHEMBL18290965 | 0.91 | MAPT (0.42) | MAPTMEN1KMT2AALDH1A1HCAR2 | |
| SCHEMBL10635286 | 0.86 | MEN1 (0.45) | MAPTMEN1KMT2AHCAR2 | |
| SCHEMBL15374659 | 0.86 | MEN1 (0.50) | MEN1KMT2APRKCA | |
| SCHEMBL6929139 | 0.83 | MEN1 (0.53) | MEN1KMT2A | |
| SCHEMBL5926286 | 0.83 | MAPT (0.38) | MAPTMEN1KMT2AALDH1A1HCAR2 | |
| SCHEMBL6929141 | 0.83 | MEN1 (0.53) | MEN1KMT2A | |
| SCHEMBL14671463 | 0.83 | MEN1 (0.53) | MEN1KMT2A | |
| SCHEMBL5926284 | 0.83 | MAPT (0.38) | MAPTMEN1KMT2AALDH1A1HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9737504-B2 | Dihydroorotic and acid dehydrogenase inhibitor | INSTITUTE OF MITOCHONDRIA SCIENCE, INC. (JP) | 2017-08-22 | — | — | US | disclosed |
| US-20160296494-A1 | DIHYDROOROTIC AND ACID DEHYDROGENASE INHIBITOR | NAI INC. | 2016-10-13 | — | — | US | disclosed |
| US-9440913-B2 | Dihydroxybenzene derivatives and antiprotozoal agent comprising same as active ingredient | NAI INC. (JP) | 2016-09-13 | — | — | US | disclosed |
| US-20150166498-A1 | DIHYDROOROTIC ACID DEHYDROGENASE INHIBITOR | NAI INC. (JP) | 2015-06-18 | — | — | US | disclosed |
| US-6514507-B2 | Administering 10-Hydroxy-2-decenoic acid and derivatives for stimulating epidermal renewal and/or combating intrinsic aging of the skin | SOCIETE L'OREAL S.A. (FR) | 2003-02-04 | — | — | US | disclosed |
| US-20030003115-A1 | HYDROXYDECENOIC ACID COMPOUNDS FOR PROMOTING DESQUAMATION/EPIDERMAL RENEWAL OF THE SKIN AND/OR COMBATING SKIN AGING | SOCIETE L'OREAL S.A. (FR) | 2003-01-02 | — | — | US | disclosed |
| US-20020086041-A1 | Hydroxydecenoic acid compounds for promoting desquamation/epidermal renewal of the skin and/or combating skin aging | MAIGNAN JEAN (FR) | 2002-07-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150166498-A1 | DIHYDROOROTIC ACID DEHYDROGENASE INHIBITOR | DHODH, DPYD, DLD | MAPT 4471/4885MEN1 3649/4885KMT2A 2734/4885 |
| US-20020086041-A1 | Hydroxydecenoic acid compounds for promoting desquamation/epidermal renewal of the skin and/or combating skin aging | HAAO, HMOX1, ALOX12 | MAPT 4523/4885MEN1 4565/4885KMT2A 3289/4885 |
| US-20160296494-A1 | DIHYDROOROTIC AND ACID DEHYDROGENASE INHIBITOR | DHODH, DPYD, DLD | MAPT 4480/4885MEN1 3767/4885KMT2A 2598/4885 |
| US-20030003115-A1 | HYDROXYDECENOIC ACID COMPOUNDS FOR PROMOTING DESQUAMATION/EPIDERMAL RENEWAL OF THE SKIN AND/OR COMBATING SKIN AGING | HAAO, HMOX1, ALOX12 | MAPT 4523/4885MEN1 4565/4885KMT2A 3289/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.