Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.61 |
| ▸ | MMP9 | P14780 | 7/20 | 0.55 |
| ▸ | MMP8 | P22894 | 7/20 | 0.55 |
| ▸ | MMP2 | P08253 | 5/20 | 0.55 |
| ▸ | MMP14 | P50281 | 1/20 | 0.54 |
| ▸ | CCKBR | P32239 | 1/20 | 0.53 |
| ▸ | TACR1 | P25103 | 1/20 | 0.52 |
| ▸ | MMP1 | P03956 | 1/20 | 0.52 |
| ▸ | MMP3 | P08254 | 1/20 | 0.52 |
| ▸ | ECE1 | P42892 | 3/20 | 0.51 |
| ▸ | ACE | P12821 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6023409 | 0.84 | MMP9 (0.61) | CTSLMMP9MMP8MMP2MMP14 | |
| SCHEMBL6019223 | 0.84 | MMP9 (0.58) | CTSLMMP9MMP8MMP2MMP14 | |
| SCHEMBL31036035 | 0.83 | ACE (0.71) | CTSLECE1ACE | |
| SCHEMBL6020973 | 0.83 | MMP9 (0.55) | CTSLMMP9MMP8MMP14CCKBR | |
| SCHEMBL6020256 | 0.83 | CTSL (0.71) | CTSLMMP9MMP8MMP14CCKBR | |
| SCHEMBL5526318 | 0.83 | CTSL (0.71) | CTSLMMP9MMP8MMP14CCKBR | |
| SCHEMBL6021223 | 0.82 | MMP9 (0.56) | CTSLMMP9MMP8MMP2MMP14 | |
| SCHEMBL6020520 | 0.82 | CCKBR (0.55) | CTSLMMP9MMP8MMP14CCKBR | |
| SCHEMBL6021321 | 0.81 | MMP9 (0.55) | CTSLMMP9MMP8MMP2MMP14 | |
| SCHEMBL6020814 | 0.81 | CCKBR (0.56) | CTSLMMP9MMP8MMP2MMP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004056755-A2 | COMPOUNDS FOR THE INHIBITION OF NON-PROTEOLYTIC ENZYMES | JERENI AG (DE) | 2004-07-08 | — | — | WO | claimed |