Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6920283 | 0.86 | FFAR4 (0.41) | MAPK1KMT2AMEN1MCL1GAA | |
| SCHEMBL6497809 | 0.82 | MCL1 (0.41) | KMT2AMEN1MCL1GAAFFAR4 | |
| SCHEMBL6922928 | 0.80 | MCL1 (0.41) | KMT2AMEN1MCL1GAAFFAR4 | |
| SCHEMBL6492273 | 0.76 | MCL1 (0.39) | KMT2AMEN1MCL1GAAFFAR4 | |
| SCHEMBL6489825 | 0.73 | L3MBTL1 (0.43) | MAPK1KMT2AMEN1MCL1GAA | |
| SCHEMBL6491177 | 0.70 | PPARD (0.40) | MCL1FFAR4FFAR1 | |
| SCHEMBL7196034 | 0.70 | MRGPRX4 (0.41) | MAPK1KMT2AMEN1 | |
| SCHEMBL6490952 | 0.70 | ALOX5AP (0.43) | KMT2AMEN1MCL1GAAFFAR4 | |
| SCHEMBL6491201 | 0.69 | MCL1 (0.43) | MCL1FFAR4ALDH1A1 | |
| SCHEMBL6920280 | 0.68 | PDE3B (0.42) | KMT2AMEN1MCL1GAAFFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004108686-A2 | BENZIMIDAZOLE COMPOUNDS HAVING HYPOGLYCEMIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-12-16 | — | — | WO | disclosed |