Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.48 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | JAK3 | P52333 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5523326 | 0.75 | CYP1A2 (0.43) | RAB9ATSHRLMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL5530347 | 0.74 | MEN1 (0.50) | GAARAB9APOLBKMT2AMEN1 | |
| SCHEMBL4599573 | 0.74 | RAB9A (0.63) | GAASLC1A2SLC1A1RAB9APOLB | |
| SCHEMBL27761563 | 0.74 | AKR1B1 (0.41) | GAAPOLBTSHRLMNAMAPT | |
| SCHEMBL2864888 | 0.74 | MAOA (0.46) | GAARAB9ATSHRKMT2AMEN1 | |
| SCHEMBL9410518 | 0.74 | MAPT (0.69) | GAASLC1A2SLC1A1RAB9APOLB | |
| SCHEMBL21937692 | 0.73 | L3MBTL1 (0.48) | POLBKMT2AMEN1LMNAL3MBTL1 | |
| SCHEMBL3815593 | 0.72 | RAB9A (0.65) | GAASLC1A2SLC1A1RAB9APOLB | |
| SCHEMBL6244722 | 0.72 | MAOA (0.47) | GAARAB9ATSHRKMT2AMEN1 | |
| SCHEMBL5526973 | 0.72 | SLC6A4 (0.50) | GAAKMT2AMEN1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004087669-A1 | NOVEL QUINOLINE, TETRAHYDROQUINAZOLINE, AND PYRIMIDINE DERIVATIVES AND METHODS OF TREATMENT RELATED TO THE USE THEREOF | TAISHO PHARMACEUTICAL CO. LTD. (JP) | 2004-10-14 | — | — | WO | disclosed |